Synthesis of new isatin derivatives for possible CNS activity

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book Synthesis of new isatin derivatives for possible CNS activity by Kiran Gangarapu, GRIN Verlag
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Kiran Gangarapu ISBN: 9783656622727
Publisher: GRIN Verlag Publication: March 25, 2014
Imprint: GRIN Verlag Language: English
Author: Kiran Gangarapu
ISBN: 9783656622727
Publisher: GRIN Verlag
Publication: March 25, 2014
Imprint: GRIN Verlag
Language: English

Master's Thesis from the year 2013 in the subject Medicine - Pharmacology, grade: 10, , course: M-Pharmacy, language: English, abstract: Isatin (1H-indole-2,3-dione) (I) was first discovered by Erdmann and Laurent in 1841, independently as a product from oxidation of indigo by nitric and chromic acids. It is a unique molecule possessing both amide and keto carbonyl groups. Apart from this, it has an active hydrogen atom attached to nitrogen (or oxygen) and an aromatic ring which was substituted at 5- and 7-positions. It exists in a tautomeric form (II) and these functional characteristics play an important role in governing the various reactions of the molecule. The C-3 carbonyl group of isatin is strongly electrophilic. As a result, isatins are readily involved in condensation and addition reactions with carbanion type nucleophiles into 3-substituted oxindoles. In general, there are three possibilities during condensation reactions. [...]

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Master's Thesis from the year 2013 in the subject Medicine - Pharmacology, grade: 10, , course: M-Pharmacy, language: English, abstract: Isatin (1H-indole-2,3-dione) (I) was first discovered by Erdmann and Laurent in 1841, independently as a product from oxidation of indigo by nitric and chromic acids. It is a unique molecule possessing both amide and keto carbonyl groups. Apart from this, it has an active hydrogen atom attached to nitrogen (or oxygen) and an aromatic ring which was substituted at 5- and 7-positions. It exists in a tautomeric form (II) and these functional characteristics play an important role in governing the various reactions of the molecule. The C-3 carbonyl group of isatin is strongly electrophilic. As a result, isatins are readily involved in condensation and addition reactions with carbanion type nucleophiles into 3-substituted oxindoles. In general, there are three possibilities during condensation reactions. [...]

More books from GRIN Verlag

Cover of the book Kinder brauchen Erziehung - Rezension by Kiran Gangarapu
Cover of the book Life-Style-Coaching für Führungskräfte by Kiran Gangarapu
Cover of the book Die Bergwerke zu Falun by Kiran Gangarapu
Cover of the book Politik in Soapoperas by Kiran Gangarapu
Cover of the book Nietzsche und das Weib. Sein Frauenbild und die Beziehung zu den Frauen by Kiran Gangarapu
Cover of the book Economic Value Added als Instrument einer wertorientierten Unternehmensführung by Kiran Gangarapu
Cover of the book Methodologische Grundlagen der teilnehmenden Beobachtung by Kiran Gangarapu
Cover of the book Die politische Ökonomie der Staatsverschuldung by Kiran Gangarapu
Cover of the book Das Spiel mit Metaphern in Beratung und Therapie by Kiran Gangarapu
Cover of the book Familiendynamik - Scheidung als Prozess? by Kiran Gangarapu
Cover of the book Hospitäler im spätmittelalterlichen Thüringen: vom kirchlichen zum bürgerlichen Hospital by Kiran Gangarapu
Cover of the book 'Der Welt Lohn' by Kiran Gangarapu
Cover of the book Unterrichtseinheit: Herbstlyrik - am Beispiel von 'Herbsttag' von Rainer Maria Rilke by Kiran Gangarapu
Cover of the book Wüstenkonvention - Die 'United Nations Convention to Combat Desertification' by Kiran Gangarapu
Cover of the book Direkte Demokratie in Italien by Kiran Gangarapu
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy