Role of Nutritional Supplements in promoting Muscle Hypertrophy

Nonfiction, Science & Nature, Science, Biological Sciences, Cytology
Cover of the book Role of Nutritional Supplements in promoting Muscle Hypertrophy by Tushar Chatterji, GRIN Verlag
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Tushar Chatterji ISBN: 9783656149811
Publisher: GRIN Verlag Publication: March 12, 2012
Imprint: GRIN Verlag Language: English
Author: Tushar Chatterji
ISBN: 9783656149811
Publisher: GRIN Verlag
Publication: March 12, 2012
Imprint: GRIN Verlag
Language: English

Essay from the year 2011 in the subject Biology - Cytology, grade: C, University of Glasgow (Institute of Cardiovascular and Medical Sciences), course: MRes Biomedical Sciences, language: English, abstract: The skeletal muscle is an integral part of our system. It not only acts as the storage reservoir of amino acids, but also serves as the site for protein synthesis and protein breakdown [36]. The rate of protein synthesis needs to exceed protein degradation to achieve muscle hypertrophy [18, 24]. The timing of protein intake, type and quantity play a significant role in achieving optimal outcomes when applied to resistance exercise [36]. Research has been going on since the past decade demonstrating the role of nutritional supplements like whey protein, soy, branched-chain amino acids (BCAAs, especially leucine) and creatine on protein synthesis before, during and after a bout of resistance exercise through careful investigations into intracellular signalling pathways like the mammalian target of rapamycin (mTOR) and its downstream targets-ribosomal protein S6 (kinase-1) and 4E binding protein (4E-BP1) [7, 18]. Intracellular signalling, amongst other variables, involves three essential components-abundant ATP in muscle for providing energy, insulin signalling and leucine (figure 1) [36, 37]. mTOR, regarded as the 'key regulator' of translation comprises mTORC1 and mTORC2 [36]. mTORC1 plays a significant role in promoting muscular hypertrophy via phosphorylation of S6K1 and 4E-BP1 which prevent binding of the eukaryotic initiation factor (eIF) 4E to 4E-BP1 allowing a complex formation with eIF4G (eIF4E-eIF4G) thus enhancing protein synthesis [5, 34]. This report highlights how whey proteins and BCAA (leucine) affect muscle protein synthesis via intracellular signalling pathways thereby contributing significant effects on muscular hypertrophy.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Essay from the year 2011 in the subject Biology - Cytology, grade: C, University of Glasgow (Institute of Cardiovascular and Medical Sciences), course: MRes Biomedical Sciences, language: English, abstract: The skeletal muscle is an integral part of our system. It not only acts as the storage reservoir of amino acids, but also serves as the site for protein synthesis and protein breakdown [36]. The rate of protein synthesis needs to exceed protein degradation to achieve muscle hypertrophy [18, 24]. The timing of protein intake, type and quantity play a significant role in achieving optimal outcomes when applied to resistance exercise [36]. Research has been going on since the past decade demonstrating the role of nutritional supplements like whey protein, soy, branched-chain amino acids (BCAAs, especially leucine) and creatine on protein synthesis before, during and after a bout of resistance exercise through careful investigations into intracellular signalling pathways like the mammalian target of rapamycin (mTOR) and its downstream targets-ribosomal protein S6 (kinase-1) and 4E binding protein (4E-BP1) [7, 18]. Intracellular signalling, amongst other variables, involves three essential components-abundant ATP in muscle for providing energy, insulin signalling and leucine (figure 1) [36, 37]. mTOR, regarded as the 'key regulator' of translation comprises mTORC1 and mTORC2 [36]. mTORC1 plays a significant role in promoting muscular hypertrophy via phosphorylation of S6K1 and 4E-BP1 which prevent binding of the eukaryotic initiation factor (eIF) 4E to 4E-BP1 allowing a complex formation with eIF4G (eIF4E-eIF4G) thus enhancing protein synthesis [5, 34]. This report highlights how whey proteins and BCAA (leucine) affect muscle protein synthesis via intracellular signalling pathways thereby contributing significant effects on muscular hypertrophy.

More books from GRIN Verlag

Cover of the book Eine handlungsorientierte Unterrichtsreihe zum systematischen Erlernen der Arbeitstechnik des Nachschlagens mit dem Wörterbuch 'Von A bis Zett' by Tushar Chatterji
Cover of the book Politische Bildung im Spannungsfeld zwischen demokratischer Verpflichtung und Meinungsfreiheit. Zum Umgang mit rechtsextremen Schülerkonzepten im Unterricht by Tushar Chatterji
Cover of the book 4.-Mai-Bewegung und kulturelle Erneuerung 1915-1921 in China by Tushar Chatterji
Cover of the book Die Kabinette von Papen und von Schleicher by Tushar Chatterji
Cover of the book Unterrichtseinheit: Zootiere - Verfassen und Lösen von Tier-Rätseln (1. Klasse) by Tushar Chatterji
Cover of the book Grundzüge der preußischen Schulreform im 19. Jahrhundert by Tushar Chatterji
Cover of the book Marketing in China by Tushar Chatterji
Cover of the book Perfume advertisement by Tushar Chatterji
Cover of the book Unbundling als Regulierungsinstrument im Eisenbahnsektor by Tushar Chatterji
Cover of the book Die Anwendung der Balanced Scorecard im Informationsmanagement by Tushar Chatterji
Cover of the book Das Frauenbild bei Rousseau by Tushar Chatterji
Cover of the book Biografiearbeit bei Menschen mit Demenz by Tushar Chatterji
Cover of the book Die Einigungskriege und die Gründung des deutschen Kaiserreichs by Tushar Chatterji
Cover of the book Die Vermittlung der Grobform des Fosbury-Flops im Sportunterricht Klasse 9 by Tushar Chatterji
Cover of the book Die Schlacht bei Tannenberg by Tushar Chatterji
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy