G Protein Signaling Mechanisms in the Retina

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Neuroscience, Science & Nature, Science, Biological Sciences, Zoology
Cover of the book G Protein Signaling Mechanisms in the Retina by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781493912186
Publisher: Springer New York Publication: September 4, 2014
Imprint: Springer Language: English
Author:
ISBN: 9781493912186
Publisher: Springer New York
Publication: September 4, 2014
Imprint: Springer
Language: English

The main purpose of this volume is to provide a focused analysis of the function of the G protein-coupled signaling pathways that operate in the interconnected network of retinal neurons as they detect and encode the information carried by light. The organization of this volume will generally follow the path of signal flow in the retina. First we will describe recent advances in understanding the phototransduction cascade of rod and cone photoreceptors, which use signaling cascade based on the GPCR rhodopsin to transduce incident light into neural activity. Chapters will be devoted to unique specializations of the two major types of photosensitive cells that comprise the predominant input for our spatial and color vision. Subsequently, the mechanisms of synaptic information encoding by retinal ON bipolar cells will be described, where the GPCR mGluR6 plays a fundamental role. Chapters in this section will examine macromolecular organization of the mGluR6 signaling pathway as well as current understanding of its function. The functional characteristics of this signaling mechanism will be explored in detail. Additionally, this section will cover the role of dopamine receptors in modulating signal transmission between photoreceptors and ON-bipolar cells. Finally, chapters will be focused on the output neurons of the inner retina, ganglion cells, where the components of the emerging GPCR melanopsin cascade in intrinsically photosensitive ganglion cells will be detailed. Collectively these mechanisms allow the retina to represent visual space over a wide range of light intensities.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The main purpose of this volume is to provide a focused analysis of the function of the G protein-coupled signaling pathways that operate in the interconnected network of retinal neurons as they detect and encode the information carried by light. The organization of this volume will generally follow the path of signal flow in the retina. First we will describe recent advances in understanding the phototransduction cascade of rod and cone photoreceptors, which use signaling cascade based on the GPCR rhodopsin to transduce incident light into neural activity. Chapters will be devoted to unique specializations of the two major types of photosensitive cells that comprise the predominant input for our spatial and color vision. Subsequently, the mechanisms of synaptic information encoding by retinal ON bipolar cells will be described, where the GPCR mGluR6 plays a fundamental role. Chapters in this section will examine macromolecular organization of the mGluR6 signaling pathway as well as current understanding of its function. The functional characteristics of this signaling mechanism will be explored in detail. Additionally, this section will cover the role of dopamine receptors in modulating signal transmission between photoreceptors and ON-bipolar cells. Finally, chapters will be focused on the output neurons of the inner retina, ganglion cells, where the components of the emerging GPCR melanopsin cascade in intrinsically photosensitive ganglion cells will be detailed. Collectively these mechanisms allow the retina to represent visual space over a wide range of light intensities.

More books from Springer New York

Cover of the book Microarrays by
Cover of the book Prions and Diseases by
Cover of the book Integrating Zooarchaeology and Paleoethnobotany by
Cover of the book Exercise and Human Reproduction by
Cover of the book Ultrasound Imaging in Reproductive Medicine by
Cover of the book Signals and Transforms in Linear Systems Analysis by
Cover of the book Microdroplet Technology by
Cover of the book Tunnel Fire Dynamics by
Cover of the book Endocrinology and Diabetes by
Cover of the book Mathematical Problem Posing by
Cover of the book Studies in Diabetes by
Cover of the book Chronic Pelvic Pain by
Cover of the book Space Systems for Disaster Warning, Response, and Recovery by
Cover of the book Primates in Fragments by
Cover of the book Practical Manual of Operative Laparoscopy and Hysteroscopy by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy