Synthesis of new isatin derivatives for possible CNS activity

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book Synthesis of new isatin derivatives for possible CNS activity by Kiran Gangarapu, GRIN Verlag
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Kiran Gangarapu ISBN: 9783656622727
Publisher: GRIN Verlag Publication: March 25, 2014
Imprint: GRIN Verlag Language: English
Author: Kiran Gangarapu
ISBN: 9783656622727
Publisher: GRIN Verlag
Publication: March 25, 2014
Imprint: GRIN Verlag
Language: English

Master's Thesis from the year 2013 in the subject Medicine - Pharmacology, grade: 10, , course: M-Pharmacy, language: English, abstract: Isatin (1H-indole-2,3-dione) (I) was first discovered by Erdmann and Laurent in 1841, independently as a product from oxidation of indigo by nitric and chromic acids. It is a unique molecule possessing both amide and keto carbonyl groups. Apart from this, it has an active hydrogen atom attached to nitrogen (or oxygen) and an aromatic ring which was substituted at 5- and 7-positions. It exists in a tautomeric form (II) and these functional characteristics play an important role in governing the various reactions of the molecule. The C-3 carbonyl group of isatin is strongly electrophilic. As a result, isatins are readily involved in condensation and addition reactions with carbanion type nucleophiles into 3-substituted oxindoles. In general, there are three possibilities during condensation reactions. [...]

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Master's Thesis from the year 2013 in the subject Medicine - Pharmacology, grade: 10, , course: M-Pharmacy, language: English, abstract: Isatin (1H-indole-2,3-dione) (I) was first discovered by Erdmann and Laurent in 1841, independently as a product from oxidation of indigo by nitric and chromic acids. It is a unique molecule possessing both amide and keto carbonyl groups. Apart from this, it has an active hydrogen atom attached to nitrogen (or oxygen) and an aromatic ring which was substituted at 5- and 7-positions. It exists in a tautomeric form (II) and these functional characteristics play an important role in governing the various reactions of the molecule. The C-3 carbonyl group of isatin is strongly electrophilic. As a result, isatins are readily involved in condensation and addition reactions with carbanion type nucleophiles into 3-substituted oxindoles. In general, there are three possibilities during condensation reactions. [...]

More books from GRIN Verlag

Cover of the book Schillers Briefe 'Über die ästhetische Erziehung des Menschen' by Kiran Gangarapu
Cover of the book Einkünftequalifikations- und Zurechnungskonflikte bei Personengesellschaften im internationalen Steuerrecht by Kiran Gangarapu
Cover of the book Synoptischer Vergleich der Perikope 'Kreuzigung' in den drei Evangelien by Kiran Gangarapu
Cover of the book Die Verrechnungspreise für immaterielle Wirtschaftsgüter im Fall der Einzelabrechnung by Kiran Gangarapu
Cover of the book Ansätze zur europäischen Vergesellschaftung by Kiran Gangarapu
Cover of the book Interkulturelle / internationale Kooperation by Kiran Gangarapu
Cover of the book International environmental laws and the concept of soft law by Kiran Gangarapu
Cover of the book Beurteilung mündlicher Leistungen by Kiran Gangarapu
Cover of the book Das Rote Wien - Die Gemeindebauten als ein 'Versailles der Arbeiter' by Kiran Gangarapu
Cover of the book Der Höhenflug des Goldpreises - Empirische Analyse und ökonomische Hintergründe by Kiran Gangarapu
Cover of the book Die Auswirkungen des Antidiskriminierungsgesetzes auf die Privatwirtschaft anhand des Gesetzentwurfes der rot-grünen Koalition by Kiran Gangarapu
Cover of the book Was den heutigen Menschen dazu veranlasst, zu glauben by Kiran Gangarapu
Cover of the book Jackson Pollock. Meister des Action Paintings by Kiran Gangarapu
Cover of the book Charlotte Kerners Jugendbuch 'Blueprint-Blaupause' als literarische Grundlage für fächerverbindenden Unterricht zum Thema 'Chancen und Grenzen des Klonens' by Kiran Gangarapu
Cover of the book Savoir vivre: Umgangsformen des polnischen Adels by Kiran Gangarapu
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy