Structure-based Design of Drugs and Other Bioactive Molecules

Tools and Strategies

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book Structure-based Design of Drugs and Other Bioactive Molecules by Arun K. Ghosh, Sandra Gemma, Wiley
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Arun K. Ghosh, Sandra Gemma ISBN: 9783527665235
Publisher: Wiley Publication: July 16, 2014
Imprint: Wiley-VCH Language: English
Author: Arun K. Ghosh, Sandra Gemma
ISBN: 9783527665235
Publisher: Wiley
Publication: July 16, 2014
Imprint: Wiley-VCH
Language: English

Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medicine. Traditionally, focus has been placed on computational, structural or synthetic methods only in isolation. This one-of-akind guide integrates all three skill sets for a complete picture of contemporary structure-based design.

This practical approach provides the tools to develop a high-affinity ligand with drug-like properties for a given drug target for which a high-resolution structure exists. The authors use numerous examples of recently developed drugs to present "best practice" methods in structurebased drug design with both newcomers and practicing researchers in mind. By way of a carefully balanced mix of theoretical background and case studies from medicinal chemistry applications, readers will quickly and efficiently master the basic skills of successful drug design.

This book is aimed at new and active medicinal chemists, biochemists, pharmacologists, natural product chemists and those working in drug discovery in the pharmaceutical industry. It is highly recommended as a desk reference to guide students in medicinal and chemical sciences as well as to aid researchers engaged in drug design today.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Drug design is a complex, challenging and innovative research area. Structure-based molecular design has transformed the drug discovery approach in modern medicine. Traditionally, focus has been placed on computational, structural or synthetic methods only in isolation. This one-of-akind guide integrates all three skill sets for a complete picture of contemporary structure-based design.

This practical approach provides the tools to develop a high-affinity ligand with drug-like properties for a given drug target for which a high-resolution structure exists. The authors use numerous examples of recently developed drugs to present "best practice" methods in structurebased drug design with both newcomers and practicing researchers in mind. By way of a carefully balanced mix of theoretical background and case studies from medicinal chemistry applications, readers will quickly and efficiently master the basic skills of successful drug design.

This book is aimed at new and active medicinal chemists, biochemists, pharmacologists, natural product chemists and those working in drug discovery in the pharmaceutical industry. It is highly recommended as a desk reference to guide students in medicinal and chemical sciences as well as to aid researchers engaged in drug design today.

More books from Wiley

Cover of the book Designing Your Organization by Arun K. Ghosh, Sandra Gemma
Cover of the book Preservation and Restoration of Tooth Structure by Arun K. Ghosh, Sandra Gemma
Cover of the book Futures Made Simple by Arun K. Ghosh, Sandra Gemma
Cover of the book Polymer Composites, Nanocomposites by Arun K. Ghosh, Sandra Gemma
Cover of the book Modelling, Simulation and Control of Two-Wheeled Vehicles, Enhanced Edition by Arun K. Ghosh, Sandra Gemma
Cover of the book JK Lasser's New Rules for Estate, Retirement, and Tax Planning by Arun K. Ghosh, Sandra Gemma
Cover of the book The Strategic Application of Information Technology in Health Care Organizations by Arun K. Ghosh, Sandra Gemma
Cover of the book The 3 Big Questions for a Frantic Family by Arun K. Ghosh, Sandra Gemma
Cover of the book Women's Health Psychology by Arun K. Ghosh, Sandra Gemma
Cover of the book A Handbook to the Reception of Classical Mythology by Arun K. Ghosh, Sandra Gemma
Cover of the book Veterinary Parasitology by Arun K. Ghosh, Sandra Gemma
Cover of the book The Oil Palm by Arun K. Ghosh, Sandra Gemma
Cover of the book Psychodynamic Formulation by Arun K. Ghosh, Sandra Gemma
Cover of the book Matchmoving by Arun K. Ghosh, Sandra Gemma
Cover of the book The Blackwell Companion to Globalization by Arun K. Ghosh, Sandra Gemma
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy