Author: | Christopher J. Bulpitt | ISBN: | 9781461563471 |
Publisher: | Springer US | Publication: | December 6, 2012 |
Imprint: | Springer | Language: | English |
Author: | Christopher J. Bulpitt |
ISBN: | 9781461563471 |
Publisher: | Springer US |
Publication: | December 6, 2012 |
Imprint: | Springer |
Language: | English |
After 13 years there are new areas to discuss and more recent trials to be included. Good clinical practice; evaluation of quality of life; measurement of the benefit:risk comparison; determination of cost- effectiveness and cost utility; stopping rules for trials; meta-analysis and subgroup analysis are all new sections. The references are expanded from 305 to 512 and include the recent advances in trial design, such as the n-of-1 trials and megatrials, and up-to-date examples to illustrate the points made in the 20 chapters.
After 13 years there are new areas to discuss and more recent trials to be included. Good clinical practice; evaluation of quality of life; measurement of the benefit:risk comparison; determination of cost- effectiveness and cost utility; stopping rules for trials; meta-analysis and subgroup analysis are all new sections. The references are expanded from 305 to 512 and include the recent advances in trial design, such as the n-of-1 trials and megatrials, and up-to-date examples to illustrate the points made in the 20 chapters.