Matrix Metalloproteinase Biology

Nonfiction, Science & Nature, Science, Biological Sciences
Cover of the book Matrix Metalloproteinase Biology by , Wiley
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781118772386
Publisher: Wiley Publication: May 27, 2015
Imprint: Wiley-Blackwell Language: English
Author:
ISBN: 9781118772386
Publisher: Wiley
Publication: May 27, 2015
Imprint: Wiley-Blackwell
Language: English

Discussing recent advances in the field of matrix metalloproteinase (MMP) research from a multidisciplinary perspective, Matrix Metalloproteinase Biologyis a collection of chapters written by leaders in the field of MMPs. The book focuses on the challenges of understanding the mechanisms substrate degradation by MMPs, as well as how these enzymes are able to degrade large, highly ordered substrates such as collagen. All topics addressed are considered in relation to disease progression including roles in cancer metastasis, rheumatoid arthritis and other inflammatory diseases.

The text first provides an overview of MMPs, focusing on the history, the development and failures of small molecule inhibitors in clinical trials, and work with TIMPS, the endogenous inhibitors of MMPs. These introductory chapters establish the foundation for later discussion of the recent progress on the design of different types of inhibitors, including novel antibody based therapeutics.The following section emphasizes research using novel methods to further the study of the MMPs. The third and final section focuses on in vivo research, particularly with respect to cancer models, degradation of the extracellular matrix, and MMP involvement in other disease states.

Written and edited by leaders in the field, Matrix Metalloproteinase Biology addresses the rapidly growth in MMP research, and will be an invaluable resource to advanced students and researchers studying cell and molecular biology.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Discussing recent advances in the field of matrix metalloproteinase (MMP) research from a multidisciplinary perspective, Matrix Metalloproteinase Biologyis a collection of chapters written by leaders in the field of MMPs. The book focuses on the challenges of understanding the mechanisms substrate degradation by MMPs, as well as how these enzymes are able to degrade large, highly ordered substrates such as collagen. All topics addressed are considered in relation to disease progression including roles in cancer metastasis, rheumatoid arthritis and other inflammatory diseases.

The text first provides an overview of MMPs, focusing on the history, the development and failures of small molecule inhibitors in clinical trials, and work with TIMPS, the endogenous inhibitors of MMPs. These introductory chapters establish the foundation for later discussion of the recent progress on the design of different types of inhibitors, including novel antibody based therapeutics.The following section emphasizes research using novel methods to further the study of the MMPs. The third and final section focuses on in vivo research, particularly with respect to cancer models, degradation of the extracellular matrix, and MMP involvement in other disease states.

Written and edited by leaders in the field, Matrix Metalloproteinase Biology addresses the rapidly growth in MMP research, and will be an invaluable resource to advanced students and researchers studying cell and molecular biology.

More books from Wiley

Cover of the book Reinvent by
Cover of the book AutoCAD 2017 and AutoCAD LT 2017 by
Cover of the book Accreditation, Certification, and Credentialing: Relevant Concerns for U.S. Evaluators by
Cover of the book What Is Your WHAT? by
Cover of the book How to Succeed with People by
Cover of the book Measuring Business Interruption Losses and Other Commercial Damages by
Cover of the book How a Second Grader Beats Wall Street by
Cover of the book Geography by
Cover of the book Extraordinary Outcomes by
Cover of the book Low-Frequency Electromagnetic Modeling for Electrical and Biological Systems Using MATLAB by
Cover of the book The Silk Road Trap by
Cover of the book Globalization by
Cover of the book The Handbook of Equity Market Anomalies by
Cover of the book Essentials of Oral and Maxillofacial Surgery by
Cover of the book The Student Newspaper Survival Guide by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy