Gene Vaccines

Nonfiction, Health & Well Being, Medical, Medical Science, Biochemistry, Immunology
Cover of the book Gene Vaccines by , Springer Vienna
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783709104392
Publisher: Springer Vienna Publication: August 31, 2011
Imprint: Springer Language: English
Author:
ISBN: 9783709104392
Publisher: Springer Vienna
Publication: August 31, 2011
Imprint: Springer
Language: English

The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.

More books from Springer Vienna

Cover of the book Hydrocephalus by
Cover of the book Extravasation of Cytotoxic Agents by
Cover of the book Creative License by
Cover of the book Dynamics of the Singing Voice by
Cover of the book Sphingolipids in Disease by
Cover of the book Glioma Cell Biology by
Cover of the book Surgery of Vertebrobasilar Aneurysms by
Cover of the book Classification of Endogenous Psychoses and their Differentiated Etiology by
Cover of the book Movement Disorders Curricula by
Cover of the book The Vertebral Artery by
Cover of the book Introduction to Programming Concepts with Case Studies in Python by
Cover of the book The Metabolic Syndrome by
Cover of the book Molekulare Sport- und Leistungsphysiologie by
Cover of the book Atlas of Color-Coded Doppler Sonography by
Cover of the book Disorders of Articulation by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy