DNA Helicases and DNA Motor Proteins

Nonfiction, Health & Well Being, Medical, Medical Science, Genetics, Science & Nature, Science, Biological Sciences, Biochemistry
Cover of the book DNA Helicases and DNA Motor Proteins by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461450375
Publisher: Springer New York Publication: November 19, 2012
Imprint: Springer Language: English
Author:
ISBN: 9781461450375
Publisher: Springer New York
Publication: November 19, 2012
Imprint: Springer
Language: English

In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or remodels nucleoprotein complexes, however, remain to be answered. It is even less understood how the helicase motors are incorporated into a wide range of genome maintenance and repair machines.

The field has reached a stage when the studies of molecular mechanisms and basic biology of helicases can and shall be integrated with the studies of development, cancer and longevity. The objective of this book is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in response to different cellular stresses and are integrated into large macromolecular assemblies to form a complex and adaptive living system.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

In recent years, a number of groundbreaking structural and mechanistic studies deepened our understanding of helicase mechanisms and established new approaches for their analyses. Many fundamental mechanistic questions ranging from the mechanism of force generation, mechanochemical coupling to distinct mechanisms by which the same enzyme translocates on DNA removing obstacles, unwinds DNA and/or remodels nucleoprotein complexes, however, remain to be answered. It is even less understood how the helicase motors are incorporated into a wide range of genome maintenance and repair machines.

The field has reached a stage when the studies of molecular mechanisms and basic biology of helicases can and shall be integrated with the studies of development, cancer and longevity. The objective of this book is to provide the first systematic overview of structure, function and regulation of DNA helicases and related molecular motors. By integrating the knowledge obtained through the diverse technical approaches ranging from single-molecule biophysics to cellular and molecular biological studies the editors aim to provide a unified view on how helicases function in the cell, are regulated in response to different cellular stresses and are integrated into large macromolecular assemblies to form a complex and adaptive living system.

More books from Springer New York

Cover of the book Modern Tools of Biophysics by
Cover of the book Reviews of Environmental Contamination and Toxicology Volume 218 by
Cover of the book Optimal Control with Aerospace Applications by
Cover of the book Age-related Macular Degeneration Diagnosis and Treatment by
Cover of the book Phytohormones: A Window to Metabolism, Signaling and Biotechnological Applications by
Cover of the book Peak Oil, Economic Growth, and Wildlife Conservation by
Cover of the book Sociobiological Perspectives on Human Development by
Cover of the book Studies on Pediatric Disorders by
Cover of the book Rhinosinusitis by
Cover of the book Howler Monkeys by
Cover of the book Social Capital and Business Development in High-Technology Clusters by
Cover of the book Around the Globe for Women's Health by
Cover of the book Advanced Biofuels and Bioproducts by
Cover of the book War, Community, and Social Change by
Cover of the book The Design and Analysis of Computer Experiments by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy