Author: | ISBN: | 9783642133329 | |
Publisher: | Springer Berlin Heidelberg | Publication: | September 30, 2010 |
Imprint: | Springer | Language: | English |
Author: | |
ISBN: | 9783642133329 |
Publisher: | Springer Berlin Heidelberg |
Publication: | September 30, 2010 |
Imprint: | Springer |
Language: | English |
The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined. Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virus particle undergoes programmed conformational changes, leading to capsid disassembly and release of small membrane-interacting peptides. A complete understanding of host cell entry by this minimal system will help elucidate the mechanisms of non-enveloped virus membrane penetration in general
The means by which non-enveloped viruses penetrate cellular membranes during cell entry remain poorly defined. Recent findings indicate several members of this group share a common mechanism of membrane penetration in which the virus particle undergoes programmed conformational changes, leading to capsid disassembly and release of small membrane-interacting peptides. A complete understanding of host cell entry by this minimal system will help elucidate the mechanisms of non-enveloped virus membrane penetration in general