Springer Netherlands: 8040 books

This book contains an extensive collection of critical reviews, from leading researchers in the field of regulated protein degradation. It covers the role of regulated proteolysis in a range of microorganisms (from Gram positive, Gram negative and pathogenic bacteria to Archaea and the Baker’s yeast Saccharomyces cerevisiae).

Overall, this book illustrates the complexities of the regulation and deregulation of genes mediated through epigenetics in the development and progression of human malignancies. All the articles have been carefully chosen to represent several cancer systems with state of our knowledge on the role...

A role for vitamin A in living organisms has been known throughout human history. In the last 100 years, the biochemical nature of vitamin A and its active derivative, retinoic acid, its physiological impact on growth processes and the essential details of its mechanism of action have been revealed...

Homeostasis. The health of an organism is influenced by external and internal changes that may lead to the loss of homeostasis. Under healthy conditions organisms compensate these changes.  If compensation fails disease ensues. Attention will be paid to lifestyle, environmental changes, genetic makeup...

Geomorphology can be defined simply as the study of landforms. Landforms are the result of the interaction between what Ritter (1978) has called the driving and resisting forces. The driving forces or processes are the methods by which energy is exerted on earth materials and include both surface,...

Blood-sucking insects are the vectors of many of the most debilitating parasites of man and his domesticated animals. In addition they are of considerable direct cost to the agricultural industry through losses in milk and meat yields, and through damage to hides and wool, etc. So, not surprisingly,...

Analysis of reliability and risk is an important and integral part of planning, construction and operation of all technical systems. To be able to perform such analyses systematically and scientifically, there is usually a need for special methods and models. This book presents the most important...

Retailing today is one of the largest, most buoyant and most competitive market sectors. The large, medium and small retailers, providers of systems are the major players in this market. The exploitation of information technology and the use of quantitative corporate models are emerging as key factors...

The past two or three decades have seen many important advances in our knowledge of the chemistry, physics, geology and biology of the oceans. It has also become apparent that in order to understand the manner in which the oceans work as a 'chemical system', it is necessary to use a framework which...

The following pages are meant for those who wish to use thyristors. The details of the physics of semiconductor materials or the design of thyristors themselves are unnecessary here but a general description of the device may help to avoid pitfalls during electric circuit design. Thyristor is the...

This book is intended as a practical manual for chemists, biologists and others whose work requires the use of pH or metal-ion buffers. Much information on buffers is scattered throughout the literature and it has been our endeavour to select data and instructions likely to be helpful in the choice...

This volume offers a scientific assessment of the effects of climatic variability and change on forest resources in the United States. Derived from a report that provides technical input to the 2013 U.S. Global Change Research Program National Climate Assessment, the book serves as a framework for...

This book develops a conception of science as a multi-dimensional practice, which includes experimental action and production, conceptual-theoretical interpretation, and formal-mathematical work. On this basis, it addresses the topical issue of scientific realism and expounds a detailed, referentially...

In this book we present a largely biochemical look at the metals of life and their functions, which we hope will be of interest to chemists and biologists as well as biochemists. The field of 'inorganic bio­ chemistry' is one of rapid change. Recent developments in our know­ ledge of the activity...