Springer Basel: 80 books
Matrix Metalloproteinase Inhibitors
Specificity of Binding and Structure-Activity Relationships
Language: English
Release Date: April 5, 2012
Matrix metalloproteinases (MMPs) are proteolytic enzymes that are involved in many physiological and pathological processes. The field of MMP research is very important due to the implications of the distinct paralogs in both human physiology and pathology. Over-activation of these enzymes results...
Tamoxifen
Pioneering Medicine in Breast Cancer
Language: English
Release Date: July 23, 2013
Tamoxifen is a pioneering medicine for the treatment and prevention of breast cancer. It is the first drug targeted therapy in cancer to be successful. Tamoxifen targets the tumor estrogen receptor. The therapy is known to have saved the lives of millions of women over the past 40 years.
This...
Gamma-Glutamyl Transpeptidases
Structure and Function
Language: English
Release Date: July 9, 2013
Gamma-Glutamyl Transpeptidases (γ-GTs) are members of the N-terminal nucleophile hydrolase superfamily, enzymes that cleave the γ-glutamyl amide bond of glutathione to liberate cysteinylglycine. The released γ-glutamyl group can be transferred to water (hydrolysis) or to amino acids or short...
Berichte zur Resistenzmonitoringstudie 2009
Resistenzsituation bei klinisch wichtigen tierpathogenen Bakterien
Language: German
Release Date: September 5, 2012
Die Anwendung von antibakteriell wirksamen Substanzen in der Veterinärmedizin erfolgt zum einen aus Gründen des Verbraucherschutzes, zum anderen zur Erhaltung der Tiergesundheit. Gleichzeitig führt jeder Einsatz von Antibiotika zur Selektion von bereits bestehenden Resistenzen, auch wird das Entstehen...
Berichte zur Lebensmittelsicherheit 2011
Zoonosen-Monitoring
Language: German
Release Date: June 5, 2013
Zoonosen sind Krankheiten bzw. Infektionen, die auf natürlichem Weg direkt oder indirekt zwischen Menschen und Tieren übertragen werden können. Mit Zoonoseerregern kontaminierte Lebensmittel stellen eine wichtige Infektionsquelle für den Menschen dar. Beim Zoonosen-Monitoring werden repräsentative...
Berichte zur Resistenzmonitoringstudie 2008
Resistenzsituation bei klinisch wichtigen tierpathogenen Bakterien Berichte gemäß § 77 Abs. 3 AMG
Language: German
Release Date: July 4, 2012
Jede Gabe von Antibiotika an Tiere fördert die Selektion bestehender Resistenzen und die Entwicklung neuer. Damit keine oder möglichst wenig resistente Keime in die menschliche Nahrungskette gelangen, braucht es Strategien. Der umfassende Bericht über Antibiotikaresistenzen bei klinisch wichtigen...
Berichte zu Pflanzenschutzmitteln 2011
Jahresbericht Pflanzenschutz-Kontrollprogramm
Language: German
Release Date: November 15, 2012
In der Bundesrepublik Deutschland überwachen die Behörden der Länder die Einhaltung der Vorschriften, die für das Inverkehrbringen und die Anwendung von Pflanzenschutzmitteln gelten. Das Pflanzenschutz-Kontrollprogramm ist ein bundesweit harmonisiertes Programm zur Überwachung pflanzenschutzrechtlicher...
Berichte zur Lebensmittelsicherheit 2011
Nationale Berichterstattung an die EU. Nationaler Rückstandskontrollplan (NRKP) und Einfuhrüberwachungsplan (EÜP)
Language: German
Release Date: July 17, 2013
Der NRKP umfasst alle der Lebensmittelgewinnung dienenden, lebenden und geschlachteten Tierarten sowie Primärerzeugnisse vom Tier wie Milch, Eier und Honig. Von 1989-1994 enthielt der NRKP Vorgaben für die Überwachung von Rindern, Schweinen, Schafen und Pferden. 1995 wurde zusätzlich auch Geflügel...
by Willi Freeden, Martin Gutting
Language: English
Release Date: February 15, 2013
Language: English
Release Date: February 15, 2013
Special functions enable us to formulate a scientific problem by reduction such that a new, more concrete problem can be attacked within a well-structured framework, usually in the context of differential equations. A good understanding of special functions provides the capacity to recognize the causality...
by Tessa Morrison
Language: English
Release Date: December 15, 2010
Language: English
Release Date: December 15, 2010
This book is about a side of Isaac Newton’s character that has not been examined – Isaac Newton as architect as demonstrated by his reconstruction of Solomon’s Temple. Although it is well known that Isaac Newton worked on the Temple, and this is mentioned in most of his biographies and in articles...
by
Language: English
Release Date: July 8, 2013
Language: English
Release Date: July 8, 2013
Logic, the discipline that explores valid reasoning, does not need to be limited to a specific form of representation but should include any form as long as it allows us to draw sound conclusions from given information. The use of diagrams has a long but unequal history in logic: The golden age of...
by
Language: English
Release Date: May 10, 2012
Language: English
Release Date: May 10, 2012
The theory of oppositions based on Aristotelian foundations of logic has been pictured in a striking square diagram which can be understood and applied in many different ways having repercussions in various fields: epistemology, linguistics, mathematics, sociology, physics. The square can also be...
Problem-Solving Methods in Combinatorics
An Approach to Olympiad Problems
Language: English
Release Date: March 20, 2013
Every year there is at least one combinatorics problem in each of the major international mathematical olympiads. These problems can only be solved with a very high level of wit and creativity. This book explains all the problem-solving techniques necessary to tackle these problems, with clear examples...
Variable Lebesgue Spaces
Foundations and Harmonic Analysis
Language: English
Release Date: February 12, 2013
This book provides an accessible introduction to the theory of variable Lebesgue spaces. These spaces generalize the classical Lebesgue spaces by replacing the constant exponent p with a variable exponent p(x). They were introduced in the early 1930s but have become the focus of renewed interest since...