Immunology category: 985 books
Therapeutic Antibody Engineering
Current and Future Advances Driving the Strongest Growth Area in the Pharmaceutical Industry
Language: English
Release Date: October 16, 2012
The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of...
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Language: English
Release Date: April 25, 2018
Language: English
Release Date: April 25, 2018
The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis...
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Language: English
Release Date: September 7, 2017
Language: English
Release Date: September 7, 2017
Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 12 discusses and details almost all aspects of the autophagy machinery in the context of health, cancer and other pathologies. Autophagy is more widely accepted as beneficial given its role in eliminating ‘toxic...
by Adrian Liston
Language: English
Release Date: October 28, 2010
Language: English
Release Date: October 28, 2010
T cells belong to a group of white blood cells called lymphocytes and play a large role in the immune response. An increased understanding of T cell immunity will provide new insights into the etiology of human autoimmune disease such as diabetes.
This volume reviews the latest developments...
by Manzoor M. Khan
Language: English
Release Date: June 21, 2016
Language: English
Release Date: June 21, 2016
The concept of immunotherapy was in infancy when the first edition was written; since then, major advances have been made, not only with several prominent clinical trials, but also with the approval of cell-based therapy by the FDA for the treatment of cancer in 2010. These events resulted in a...
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Language: English
Release Date: February 18, 2015
Language: English
Release Date: February 18, 2015
Over the last several years the field of humanized mice has matured and developed into an essential component of translational research for HIV/AIDS. Humanized mice serve both as vehicles for discovery and as highly sophisticated platforms for biomedical research. In addition, humanized mice have...
Myasthenia Gravis
Disease Mechanism and Immunointervention
Language: English
Release Date: December 6, 2012
Autoimmune myasthenia gravis (MG) is a classical autoimmune disease, for which the target antigen, nicotinic acetylcholine receptor, has been cloned, sequenced and biochemically characterized. Antibodies to acetylcholine receptors destroy acetylcholine receptor at the neuromuscular junction, thus...
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Language: English
Release Date: March 3, 2013
Language: English
Release Date: March 3, 2013
Development of new-generation vaccines is now more challenging than ever, as identifying, purifying and evaluating vaccine antigens is a complex undertaking. Most importantly, once the relevant antigens have been identified, key focus then shifts to the development of suitable delivery systems and...
Tumor Microenvironment and Cellular Stress
Signaling, Metabolism, Imaging, and Therapeutic Targets
Language: English
Release Date: November 23, 2013
The collection of chapters in this proceeding volume reflects the latest research presented at the Aegean meeting on Tumor Microenvironment and Cellular Stress held in Crete in Fall of 2012. The book provides critical insight to how the tumor microenvironment affects tumor metabolism, cell stemness,...
Experimental Approaches for the Investigation of Innate Immunity
The Human Innate Immunity Handbook
Language: English
Release Date: January 15, 2016
The recent explosion of information in innate immune pathways for recognition, effect or responses, and genetic regulation has given impetus to investigations into analogous pathways in the human immune response, which in turn has produced attendant insights into both normal physiology and immunopathology....
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Language: English
Release Date: January 4, 2013
Language: English
Release Date: January 4, 2013
First, systems biology is an inter-disciplinary approach, requiring the combined talents of biologists, mathematicians, and computer scientists. Second, systems biology is holistic, with the goal of obtaining a comprehensive understanding of the workings of biological systems. This is achieved through...
Cellular Therapy of Cancer
Development of Gene Therapy Based Approaches
Language: English
Release Date: May 5, 2014
Cancer research has progressed enormously in recent years. This review volume will address recent findings in the area of T-cell therapy for cancer, including use of tumour infiltrating lymphocytes (TILs) as a therapy for melanoma, choice of target antigens, advances in engineered receptors, methods...
Selenium
Its Molecular Biology and Role in Human Health
Language: English
Release Date: November 13, 2011
Many health benefits have been attributed to selenium that include preventing various forms of cancer (e.g., colon cancer, prostate cancer, lung cancer and liver cancer), heart disease and other cardiovascular and muscle disorders, inhibiting viral expression, delaying the progression of acquired...
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Language: English
Release Date: December 14, 2016
Language: English
Release Date: December 14, 2016
The book describes the major degenerative processes and pathologies exacerbated by senescence and how they can be alleviated through retardation of cellular aging. Topics discussed include neurodegenerative disease, protein oxidation, cerebrovascular disease, particle-induced inflammation and cardiovascular...