Aging Research in Yeast

Nonfiction, Health & Well Being, Medical, Specialties, Geriatrics, Science & Nature, Science, Biological Sciences
Cover of the book Aging Research in Yeast by , Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9789400725614
Publisher: Springer Netherlands Publication: November 19, 2011
Imprint: Springer Language: English
Author:
ISBN: 9789400725614
Publisher: Springer Netherlands
Publication: November 19, 2011
Imprint: Springer
Language: English

This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain). Most mechanisms of aging are studied in yeast. Among them, this book discusses: mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses; the role of autophagy and mitophagy; the relationship of apoptosis to aging processes; the role of asymmetric segregation of damage in replicative aging; the role of replication stress; and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This volume includes contributions by the leading experts in the field of yeast aging. Budding yeast (Saccharomyces cerevisiae) and other fungal organisms provide models for aging research that are relevant to organismic aging and to the aging processes occurring in the human body. Replicative aging, in which only the mother cell ages while the daughter cell resets the clock to zero is a model for the aging of stem cell populations in humans, while chronological aging (measured by survival in stationary phase) is a model for the aging processes in postmitotic cells (for instance, neurons of the brain). Most mechanisms of aging are studied in yeast. Among them, this book discusses: mitochondrial theories of aging, emphasizing oxidative stress and retrograde responses; the role of autophagy and mitophagy; the relationship of apoptosis to aging processes; the role of asymmetric segregation of damage in replicative aging; the role of replication stress; and the role of the cytoskeleton in aging. Modern methods of yeast genetics and genomics are described that can be used to search for aging-specific functions in a genome-wide unbiased fashion. The similarities in the pathology of senescence (studied in yeast) and of cancer cells, including genome instability, are examined.

More books from Springer Netherlands

Cover of the book The Dawn of Cognitive Science by
Cover of the book Quality of Life in South Africa by
Cover of the book Desmoid Tumors by
Cover of the book Proceedings of the International Conference on IT Convergence and Security 2011 by
Cover of the book Modelling by
Cover of the book Theory of Digital Automata by
Cover of the book Evolution of the Atmosphere, Fire and the Anthropocene Climate Event Horizon by
Cover of the book Crime, HIV and Health: Intersections of Criminal Justice and Public Health Concerns by
Cover of the book The Natural Philosophy of Leibniz by
Cover of the book The Regularized Fast Hartley Transform by
Cover of the book Cholesterol and Beyond by
Cover of the book Children and the Good Life by
Cover of the book Father Involvement in Young Children’s Lives by
Cover of the book The EU Charter of Fundamental Rights by
Cover of the book Logic, Truth and the Modalities by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy