21st Century Progressive Supranuclear Palsy (PSP) Sourcebook: Clinical Data for Patients, Families, and Physicians - Steele-Richardson-Olszewski Syndrome, Symptoms, Supportive Therapies, Parkinson's

This comprehensive ebook provides authoritative information and practical advice from the nation's health experts about Progressive Supranuclear Palsy (PSP), also known as Steele-Richardson-Olszewski syndrome. Starting with the basics, and advancing to detailed patient-oriented and physician-quality information, the 21st Century Sourcebook series gives empowered patients, families, caregivers, nurses, and physicians the information they need to understand PSP. There is extensive coverage of symptoms, diagnosis, medical testing, clinical research, supportive therapies, and much more. Because of its relationship to Parkinson's Disease, there is also supplemental coverage of PD.

This edition includes our exclusive Guide to Leading Medical Websites with updated links to 81 of the best sites for medical information, which let you quickly check for updates from the government and the best commercial portals, news sites, reference/textbook/non-commercial portals, and health organizations.

Progressive supranuclear palsy (PSP) is a rare brain disorder that causes serious and progressive problems with control of gait and balance, along with complex eye movement and thinking problems. One of the classic signs of the disease is an inability to aim the eyes properly, which occurs because of lesions in the area of the brain that coordinates eye movements. Some individuals describe this effect as a blurring. Affected individuals often show alterations of mood and behavior, including depression and apathy as well as progressive mild dementia.

The disorder's long name indicates that the disease begins slowly and continues to get worse (progressive), and causes weakness (palsy) by damaging certain parts of the brain above pea-sized structures called nuclei that control eye movements (supranuclear).

PSP was first described as a distinct disorder in 1964, when three scientists published a paper that distinguished the condition from Parkinson's disease. It is sometimes referred to as Steele-Richardson-Olszewski syndrome, reflecting the combined names of the scientists who defined the disorder. Although PSP gets progressively worse, no one dies from PSP itself.

Approximately 20,000 Americans—or one in every 100,000 people over the age of 60—have PSP, making it much less common than Parkinson's disease, which affects more than 500,000 Americans. Affected individuals are usually middle-aged or elderly, and men are affected more often than women. PSP is often difficult to diagnose because its symptoms can be very much like those of other, more common movement disorders, and because some of the most characteristic symptoms may develop late or not at all. In rare cases, the symptoms will be more similar to those of Parkinson disease, and some individuals may even have tremors. This version is often referred to as “Parkinsonian PSP” or PSP-P.