Targeting Protein Kinases for Cancer Therapy

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book Targeting Protein Kinases for Cancer Therapy by David J. Matthews, Mary E. Gerritsen, Wiley
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Author: David J. Matthews, Mary E. Gerritsen ISBN: 9781118210772
Publisher: Wiley Publication: September 20, 2011
Imprint: Wiley Language: English
Author: David J. Matthews, Mary E. Gerritsen
ISBN: 9781118210772
Publisher: Wiley
Publication: September 20, 2011
Imprint: Wiley
Language: English

An expert guide to targeting protein kinases in cancer therapy

Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication.

Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes:

  • Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research
  • Focus on small molecule inhibitors as well as other therapeutic modalities
  • Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market

Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

An expert guide to targeting protein kinases in cancer therapy

Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication.

Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes:

Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.

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