RNA 3D Structure Analysis and Prediction

Nonfiction, Science & Nature, Science, Biological Sciences, Biochemistry
Cover of the book RNA 3D Structure Analysis and Prediction by , Springer Berlin Heidelberg
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Author: ISBN: 9783642257407
Publisher: Springer Berlin Heidelberg Publication: June 5, 2012
Imprint: Springer Language: English
Author:
ISBN: 9783642257407
Publisher: Springer Berlin Heidelberg
Publication: June 5, 2012
Imprint: Springer
Language: English

With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone.  This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.

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With the dramatic increase in RNA 3D structure determination in recent years, we now know that RNA molecules are highly structured. Moreover, knowledge of RNA 3D structures has proven crucial for understanding in atomic detail how they carry out their biological functions. Because of the huge number of potentially important RNA molecules in biology, many more than can be studied experimentally, we need theoretical approaches for predicting 3D structures on the basis of sequences alone.  This volume provides a comprehensive overview of current progress in the field by leading practitioners employing a variety of methods to model RNA 3D structures by homology, by fragment assembly, and by de novo energy and knowledge-based approaches.

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