Patho-Epigenetics of Infectious Disease

Nonfiction, Science & Nature, Science, Biological Sciences, Microbiology, Health & Well Being, Medical, Ailments & Diseases, Infectious Diseases, General
Cover of the book Patho-Epigenetics of Infectious Disease by , Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783319247380
Publisher: Springer International Publishing Publication: December 11, 2015
Imprint: Springer Language: English
Author:
ISBN: 9783319247380
Publisher: Springer International Publishing
Publication: December 11, 2015
Imprint: Springer
Language: English

Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell type-specific gene expression in all developmental stages of the life of an organism. Carefully orchestrated processes, such as DNA methylation and a plenitude of specific histone modifications secure the faithful transmission of gene expression patterns to progeny cells. Upon chronic infection, the epigenetic cellular balance can become disrupted and, in the long run, through the epigenetic reprogramming of host cell genomes, contribute to the malignant conversion of formerly healthy cells, in many cases preceded by the establishment of an epigenetic field of cancerization. The present volume undertakes to highlight the interactions of infectious pathogens and their effector molecules with the epigenetic regulatory machinery of the cell. Clearly, the recent take-off of epigenetics research did not leave Research on Infectious Diseases and Infection-Associated Cancer untouched. This resulted in a great many of clinically relevant data on understanding the molecular mechanisms of chronic infectious disease. Infectious pathogen- and disease-specific epigenetic alterations are already being used for the early detection of malignant disease and for the prediction of chemotherapy resistance or response to treatment.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Epigenetic modification of cellular genomes is a fascinating means of regulating tissue- and cell type-specific gene expression in all developmental stages of the life of an organism. Carefully orchestrated processes, such as DNA methylation and a plenitude of specific histone modifications secure the faithful transmission of gene expression patterns to progeny cells. Upon chronic infection, the epigenetic cellular balance can become disrupted and, in the long run, through the epigenetic reprogramming of host cell genomes, contribute to the malignant conversion of formerly healthy cells, in many cases preceded by the establishment of an epigenetic field of cancerization. The present volume undertakes to highlight the interactions of infectious pathogens and their effector molecules with the epigenetic regulatory machinery of the cell. Clearly, the recent take-off of epigenetics research did not leave Research on Infectious Diseases and Infection-Associated Cancer untouched. This resulted in a great many of clinically relevant data on understanding the molecular mechanisms of chronic infectious disease. Infectious pathogen- and disease-specific epigenetic alterations are already being used for the early detection of malignant disease and for the prediction of chemotherapy resistance or response to treatment.

More books from Springer International Publishing

Cover of the book Information Literacy in Everyday Life by
Cover of the book After-School Programs to Promote Positive Youth Development by
Cover of the book Recent Developments and Achievements in Biocybernetics and Biomedical Engineering by
Cover of the book Isolation and Molecular Characterization of Circulating Tumor Cells by
Cover of the book Gold Nanostars by
Cover of the book The Tree of Knowledge by
Cover of the book Pathophysiology and Pharmacotherapy of Cardiovascular Disease by
Cover of the book Neuropathology Simplified by
Cover of the book The FDA for Doctors by
Cover of the book Animals in Tillich's Philosophical Theology by
Cover of the book The sine-Gordon Model and its Applications by
Cover of the book Resisting Carceral Violence by
Cover of the book Quality Assurance in Asia-Pacific Universities by
Cover of the book Sediment Compaction and Applications in Petroleum Geoscience by
Cover of the book Universal Access in Human-Computer Interaction. Interaction Techniques and Environments by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy