Linkage Thermodynamics of Macromolecular Interactions
Nonfiction, Science & Nature, Science, Other Sciences, Molecular Biology, Biological Sciences, Biochemistry
| Author: | Frederic M. Richards, David S. Eisenberg, Peter S. Kim, Enrico Di Cera | ISBN: | 9780080582245 |
| Publisher: | Elsevier Science | Publication: | June 24, 1998 |
| Imprint: | Language: | English |
| Author: | Frederic M. Richards, David S. Eisenberg, Peter S. Kim, Enrico Di Cera |
| ISBN: | 9780080582245 |
| Publisher: | Elsevier Science |
| Publication: | June 24, 1998 |
| Imprint: | |
| Language: | English |
This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.
This volume commemorates the 50th anniversary of the appearance in Volume 4 in 1948 of Dr. Jeffries Wyman's famous paper in which he "laid down" the foundations of linkage thermodynamics. Experts in this area contribute articles on the state-of-the-art of this important field and on new developments of the original theory. Among the topics covered in this volume are electrostatic contributions to molecular free energies in solution; site-specific analysis of mutational effects in proteins; allosteric transitions of the acetylcholine receptor; and deciphering the molecular code of hemoglobin allostery.
