Histopathology of Preclinical Toxicity Studies

Interpretation and Relevance in Drug Safety Evaluation

Nonfiction, Health & Well Being, Medical, Specialties, Toxicology, Medical Science, Pharmacology
Cover of the book Histopathology of Preclinical Toxicity Studies by Peter Greaves, Elsevier Science
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Author: Peter Greaves ISBN: 9780080471303
Publisher: Elsevier Science Publication: March 23, 2007
Imprint: Elsevier Science Language: English
Author: Peter Greaves
ISBN: 9780080471303
Publisher: Elsevier Science
Publication: March 23, 2007
Imprint: Elsevier Science
Language: English

This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.

NEW TO THE THIRD EDITION:
* Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies
* General comments to each chapter about the relevance of pathological findings to humans
* Provides essential information that can help decide the relevance of particular lesions for patients

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This work covers effectively all aspects of drug-induced pathology that may be encountered within preclinical toxicity studies. It fills a gap in the pathology literature relating to the preclinical safety assessment of new medicines. It systematically describes, in one volume, both spontaneous and drug induced pathology on an organ by organ basis. Information relevant to understanding the nature of pathological changes in pre-clinical studies and assessment of their relevance to the clinical investigation of new drugs is also covered. Numerous colour photographs are included that highlight and embellish the histopathological features that are described. It also contains many pertinent references to both human and animal pathology forming an essential basis for the assessment of drug-induced pathology.

NEW TO THE THIRD EDITION:
* Covers drug induced pathology in preclinical (animal) studies and their relevance for patients or volunteers in clinical studies
* General comments to each chapter about the relevance of pathological findings to humans
* Provides essential information that can help decide the relevance of particular lesions for patients

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