GnRH: The Master Molecule of Reproduction

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Neuroscience, Veterinary Medicine, Science & Nature, Science
Cover of the book GnRH: The Master Molecule of Reproduction by Andrea C. Gore, Springer US
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Andrea C. Gore ISBN: 9781475735659
Publisher: Springer US Publication: March 9, 2013
Imprint: Springer Language: English
Author: Andrea C. Gore
ISBN: 9781475735659
Publisher: Springer US
Publication: March 9, 2013
Imprint: Springer
Language: English

Gonadotropin-releasing hormone (GnRH) cells are the key regulators of reproductive function in all vertebrate organisms. The GnRH molecule is synthesized in a small number of neurons in rostral hypothalamic regions of the brain. In mammals, these neurons release the GnRH decapeptide into the portal capillary system leading to the anterior pituitary gland. There, GnRH causes the release of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn act upon the gonads to stimulate their maturation, and to cause synthesis of sex steroid hormones, estrogen, progesterone and testosterone. Although each of the levels of the hypothalamic-pituitary-gonadal axis is critical for reproductive function, GnRH neurons play the primary role in the control of reproductive maturation and adult reproductive function, and may even play a role in reproductive senescence.

Since its discovery in 1970, there has been intense interest in GnRH-producing neurons, with more than 8000 papers and chapters in the last decade alone. Despite this activity of research in basic and clinical science, there has never been a book written specifically on GnRH neurons. GnRH: The Master Molecule of Reproduction aims to bring together the large and diverse literature of both laboratory and applied research that focuses on these unique cells.

This book will provide basic background into reproductive neuroendocrinology, as well as specifics regarding the role of GnRH neurons in the control of reproduction. Students studying endocrinology, reproduction, neuroendocrinology or molecular endocrinology will benefit from this book. In addition, this book will take a multi-species approach which will be useful both to basic researchers as well as clinicians. Whenever possible, species differences and similarities will be presented, and if possible, studies on humans, or the clinical relevance of basic research findings to humans will be discussed (such as the treatment of reproductive disorders such as abnormalities in pubertal development, or infertility).

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Gonadotropin-releasing hormone (GnRH) cells are the key regulators of reproductive function in all vertebrate organisms. The GnRH molecule is synthesized in a small number of neurons in rostral hypothalamic regions of the brain. In mammals, these neurons release the GnRH decapeptide into the portal capillary system leading to the anterior pituitary gland. There, GnRH causes the release of the gonadotropins, luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which in turn act upon the gonads to stimulate their maturation, and to cause synthesis of sex steroid hormones, estrogen, progesterone and testosterone. Although each of the levels of the hypothalamic-pituitary-gonadal axis is critical for reproductive function, GnRH neurons play the primary role in the control of reproductive maturation and adult reproductive function, and may even play a role in reproductive senescence.

Since its discovery in 1970, there has been intense interest in GnRH-producing neurons, with more than 8000 papers and chapters in the last decade alone. Despite this activity of research in basic and clinical science, there has never been a book written specifically on GnRH neurons. GnRH: The Master Molecule of Reproduction aims to bring together the large and diverse literature of both laboratory and applied research that focuses on these unique cells.

This book will provide basic background into reproductive neuroendocrinology, as well as specifics regarding the role of GnRH neurons in the control of reproduction. Students studying endocrinology, reproduction, neuroendocrinology or molecular endocrinology will benefit from this book. In addition, this book will take a multi-species approach which will be useful both to basic researchers as well as clinicians. Whenever possible, species differences and similarities will be presented, and if possible, studies on humans, or the clinical relevance of basic research findings to humans will be discussed (such as the treatment of reproductive disorders such as abnormalities in pubertal development, or infertility).

More books from Springer US

Cover of the book Comprehensive Handbook of Cognitive Therapy by Andrea C. Gore
Cover of the book The Group Effect by Andrea C. Gore
Cover of the book Behavior and the Natural Environment by Andrea C. Gore
Cover of the book Theory and Research in Behavioral Pediatrics by Andrea C. Gore
Cover of the book Treating the Criminal Offender by Andrea C. Gore
Cover of the book Engineering Flow and Heat Exchange by Andrea C. Gore
Cover of the book Optical Networks by Andrea C. Gore
Cover of the book Biostatistical Applications in Cancer Research by Andrea C. Gore
Cover of the book Current Ornithology by Andrea C. Gore
Cover of the book Ultra-Wideband and 60 GHz Communications for Biomedical Applications by Andrea C. Gore
Cover of the book Evoked Brain Potentials in Psychiatry by Andrea C. Gore
Cover of the book Trends in Youth Development by Andrea C. Gore
Cover of the book Current Problems in Fertility by Andrea C. Gore
Cover of the book The Psychopathology of Language and Cognition by Andrea C. Gore
Cover of the book Avian Leukosis by Andrea C. Gore
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy