Gene Transfer and the Ethics of First-in-Human Research

Lost in Translation

Nonfiction, Reference & Language, Law, Medical Law & Legislation, Health & Well Being, Medical, Reference, Ethics
Cover of the book Gene Transfer and the Ethics of First-in-Human Research by Jonathan Kimmelman, Cambridge University Press
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Author: Jonathan Kimmelman ISBN: 9780511847653
Publisher: Cambridge University Press Publication: October 29, 2009
Imprint: Cambridge University Press Language: English
Author: Jonathan Kimmelman
ISBN: 9780511847653
Publisher: Cambridge University Press
Publication: October 29, 2009
Imprint: Cambridge University Press
Language: English

Human gene transfer is widely regarded as one of the most promising technologies for the treatment of a variety of disorders, but it presents practitioners with a variety of difficult ethical questions. Gene Transfer and the Ethics of First-in-Human Research examines the ethical and policy dimensions of testing interventions in human beings for the first time. The book discusses the difficult ethical challenges that arise from attempting to translate laboratory discoveries into clinical applications. These range from which available techniques to use, when to initiate human testing, questions of consent, expectation in public arenas, how to define acceptable risk, and the inclusion of vulnerable or disadvantaged subjects in early phase trials. This book is relevant to ethicists, legal practitioners, policy makers, geneticists and clinicians involved in clinical trials of new medical interventions.

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Human gene transfer is widely regarded as one of the most promising technologies for the treatment of a variety of disorders, but it presents practitioners with a variety of difficult ethical questions. Gene Transfer and the Ethics of First-in-Human Research examines the ethical and policy dimensions of testing interventions in human beings for the first time. The book discusses the difficult ethical challenges that arise from attempting to translate laboratory discoveries into clinical applications. These range from which available techniques to use, when to initiate human testing, questions of consent, expectation in public arenas, how to define acceptable risk, and the inclusion of vulnerable or disadvantaged subjects in early phase trials. This book is relevant to ethicists, legal practitioners, policy makers, geneticists and clinicians involved in clinical trials of new medical interventions.

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