Diversity-Oriented Synthesis

Basics and Applications in Organic Synthesis, Drug Discovery, and Chemical Biology

Nonfiction, Health & Well Being, Medical, Medical Science, Biochemistry, Science & Nature, Science, Chemistry, Organic, Biological Sciences
Cover of the book Diversity-Oriented Synthesis by Andrea Trabocchi, Wiley
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Andrea Trabocchi ISBN: 9781118618141
Publisher: Wiley Publication: June 17, 2013
Imprint: Wiley Language: English
Author: Andrea Trabocchi
ISBN: 9781118618141
Publisher: Wiley
Publication: June 17, 2013
Imprint: Wiley
Language: English

Discover an enhanced synthetic approach to developing and screening chemical compound libraries

Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology.

Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book:

  • Offers key chemical methods for the generation of small molecules using diversity-oriented principles, including peptidomimetics and macrocycles
  • Expands on the concept of diversity-oriented synthesis by describing chemical libraries
  • Provides modern approaches to screening diversity-oriented synthetic libraries, including high-throughput and high-content screening, small molecule microarrays, and smart screening assays
  • Presents the applications of diversity-oriented synthetic libraries and small molecules in drug discovery and chemical biology, reporting the results of key studies and forecasting the role of diversity-oriented synthesis in future biomedical research

This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications.

Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Discover an enhanced synthetic approach to developing and screening chemical compound libraries

Diversity-oriented synthesis is a new paradigm for developing large collections of structurally diverse small molecules as probes to investigate biological pathways. This book presents the most effective methods in diversity-oriented synthesis for creating small molecule collections. It offers tested and proven strategies for developing diversity-oriented synthetic libraries and screening methods for identifying ligands. Lastly, it explores some promising new applications based on diversity-oriented synthesis that have the potential to dramatically advance studies in drug discovery and chemical biology.

Diversity-Oriented Synthesis begins with an introductory chapter that explores the basics, including a discussion of the relationship between diversity-oriented synthesis and classic combinatorial chemistry. Divided into four parts, the book:

This book has been written and edited by leading international experts in organic synthesis and its applications. Their contributions are based on a thorough review of the current literature as well as their own firsthand experience developing synthetic methods and applications.

Clearly written and extensively referenced, Diversity-Oriented Synthesis introduces novices to this highly promising field of research and serves as a springboard for experts to advance their own research studies and develop new applications.

More books from Wiley

Cover of the book Sold on Language by Andrea Trabocchi
Cover of the book The Psychology of Diversity by Andrea Trabocchi
Cover of the book Inflammation by Andrea Trabocchi
Cover of the book This is Social Media by Andrea Trabocchi
Cover of the book Die funf entscheidenden Fragen des Managements by Andrea Trabocchi
Cover of the book Political Philosophy by Andrea Trabocchi
Cover of the book Feminist Literary History by Andrea Trabocchi
Cover of the book Managing Technological Innovation by Andrea Trabocchi
Cover of the book Commercial Real Estate Investing by Andrea Trabocchi
Cover of the book Geotechnik by Andrea Trabocchi
Cover of the book Don't Bring It to Work by Andrea Trabocchi
Cover of the book The Optimism Advantage by Andrea Trabocchi
Cover of the book Probiotics For Dummies by Andrea Trabocchi
Cover of the book Trademark Valuation by Andrea Trabocchi
Cover of the book Frequently Asked Questions in Islamic Finance by Andrea Trabocchi
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy