Mathematical Modeling and Experimental Observations
by
Iman Tavassoly
Language: English
Release Date: February 16, 2015
This interdisciplinary thesis introduces a systems biology approach to study the cell fate decision mediated by autophagy. A mathematical model of interaction between Autophagy and Apoptosis in mammalian cells is proposed. In this dynamic model autophagy acts as a gradual response to stress (Rheostat)...