Apolipoprotein Mimetics in the Management of Human Disease

Nonfiction, Health & Well Being, Medical, Medical Science, Biochemistry, Specialties, Internal Medicine, Cardiology, Science & Nature, Science
Cover of the book Apolipoprotein Mimetics in the Management of Human Disease by , Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783319173504
Publisher: Springer International Publishing Publication: June 15, 2015
Imprint: Adis Language: English
Author:
ISBN: 9783319173504
Publisher: Springer International Publishing
Publication: June 15, 2015
Imprint: Adis
Language: English

This comprehensive book provides not only the stages in the development of this unique and specialized field but also updates on the current state of research and development of apolipoprotein mimetics as therapeutic modalities for various lipid-mediated disorders. The book consists of 11 chapters all written by leading scientists from well-reputed laboratories in the USA. After an introduction by Dr. Godfrey Getz, Professor of Medicine at the University of Chicago and the Associate Editor of the Journal Lipid Research, the book presents a narration of how a theory can lead to the discovery of treatment modalities to several devastating diseases such as diabetes, Alzheimer’s disease, arthritis; asthma; atherosclerosis, chronic rejection of transplanted hearts and cancer.

Present therapies for most of these diseases are not adequate. Using the models of two long anti-atherogenic and anti-inflammatory proteins (apolipoprotein A-I and apolipoprotein E with 243 and 299 amino acids, respectively) short mimetic peptides of 18 to 28 amino acid residues in length, which can be produced either synthetically or genetically in edible fruits and vegetables, have been shown to exert profound biological effects in a large number of animal models of diseases.

The book also presents novel ideas, highly unexpected mechanisms of action in animal models and even in initial clinical studies in humans, which can lead to additional improvements in basic and clinical research in biological science. All the chapters are written by experts in their respective fields who have contributed immensely to the literature. This is the first compendium of this growing field presented in the form of a book.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This comprehensive book provides not only the stages in the development of this unique and specialized field but also updates on the current state of research and development of apolipoprotein mimetics as therapeutic modalities for various lipid-mediated disorders. The book consists of 11 chapters all written by leading scientists from well-reputed laboratories in the USA. After an introduction by Dr. Godfrey Getz, Professor of Medicine at the University of Chicago and the Associate Editor of the Journal Lipid Research, the book presents a narration of how a theory can lead to the discovery of treatment modalities to several devastating diseases such as diabetes, Alzheimer’s disease, arthritis; asthma; atherosclerosis, chronic rejection of transplanted hearts and cancer.

Present therapies for most of these diseases are not adequate. Using the models of two long anti-atherogenic and anti-inflammatory proteins (apolipoprotein A-I and apolipoprotein E with 243 and 299 amino acids, respectively) short mimetic peptides of 18 to 28 amino acid residues in length, which can be produced either synthetically or genetically in edible fruits and vegetables, have been shown to exert profound biological effects in a large number of animal models of diseases.

The book also presents novel ideas, highly unexpected mechanisms of action in animal models and even in initial clinical studies in humans, which can lead to additional improvements in basic and clinical research in biological science. All the chapters are written by experts in their respective fields who have contributed immensely to the literature. This is the first compendium of this growing field presented in the form of a book.

More books from Springer International Publishing

Cover of the book Evaluation and Management of Autonomic Disorders by
Cover of the book The Intrinsic Bispectrum of the Cosmic Microwave Background by
Cover of the book Cruel, Inhuman or Degrading Treatment? by
Cover of the book Entertainment Computing and Serious Games by
Cover of the book Minimum Action Curves in Degenerate Finsler Metrics by
Cover of the book Animal Models of Acute Neurological Injury by
Cover of the book Man–Machine Interactions 4 by
Cover of the book Video Astronomy on the Go by
Cover of the book Kinetic Theory of Nonequilibrium Ensembles, Irreversible Thermodynamics, and Generalized Hydrodynamics by
Cover of the book Advances in Computational Plasticity by
Cover of the book Rational Extended Thermodynamics beyond the Monatomic Gas by
Cover of the book Alice Munro by
Cover of the book Physiology Question-Based Learning by
Cover of the book Dignity in the Workplace by
Cover of the book Pediatric Neurotoxicology by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy