Vesicle Trafficking in Cancer

Nonfiction, Science & Nature, Science, Other Sciences, Molecular Biology, Health & Well Being, Medical, Specialties, Oncology
Cover of the book Vesicle Trafficking in Cancer by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461465287
Publisher: Springer New York Publication: April 2, 2013
Imprint: Springer Language: English
Author:
ISBN: 9781461465287
Publisher: Springer New York
Publication: April 2, 2013
Imprint: Springer
Language: English

Endocytosis and vesicular trafficking determine the landscape of the cell’s exterior, namely the density of surface molecules, such as receptors for growth factors and cytokines, adhesion molecules like integrins and cadherins, and a plethora of nutrient carriers. Hence, endocytosis is involved in signal transduction, cell adhesion and migration, as well as metabolism. To exploit these fundamental processes, malignancies subtly and multiply manipulate the endocytosis and the subsequent trafficking of protein cargoes. This is achieved by simultaneously altering the cytoskeleton, vesicle budding, cargo sorting and intracellular degradation. By highlighting the underlying molecular processes and concentrating on specific examples, this book reviews the recent emergence of derailed endocytosis and vesicular trafficking as a landmark of cancer. In-depth understanding of this common feature of tumors might lead the way to drug-induced strategies, able to rectify intracellular trafficking in cancer.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Endocytosis and vesicular trafficking determine the landscape of the cell’s exterior, namely the density of surface molecules, such as receptors for growth factors and cytokines, adhesion molecules like integrins and cadherins, and a plethora of nutrient carriers. Hence, endocytosis is involved in signal transduction, cell adhesion and migration, as well as metabolism. To exploit these fundamental processes, malignancies subtly and multiply manipulate the endocytosis and the subsequent trafficking of protein cargoes. This is achieved by simultaneously altering the cytoskeleton, vesicle budding, cargo sorting and intracellular degradation. By highlighting the underlying molecular processes and concentrating on specific examples, this book reviews the recent emergence of derailed endocytosis and vesicular trafficking as a landmark of cancer. In-depth understanding of this common feature of tumors might lead the way to drug-induced strategies, able to rectify intracellular trafficking in cancer.

More books from Springer New York

Cover of the book Air Pollution and Forests by
Cover of the book Handbook of Mindfulness and Self-Regulation by
Cover of the book Molecular and Cellular Mechanobiology by
Cover of the book Systems Biology of Tumor Dormancy by
Cover of the book Education and Support Programs for Caregivers by
Cover of the book Music and Child Development by
Cover of the book Affinographs by
Cover of the book Complex Systems and Society by
Cover of the book Brownian Dynamics at Boundaries and Interfaces by
Cover of the book Becoming a Family Physician by
Cover of the book Attention Deficit Hyperactivity Disorder Handbook by
Cover of the book The Internet of Things by
Cover of the book Obesity and Fertility by
Cover of the book Network Reliability in Practice by
Cover of the book ITIL® 2011 At a Glance by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy