Urine Proteomics in Kidney Disease Biomarker Discovery

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Nephrology, Science & Nature, Science, Biological Sciences, Biochemistry
Cover of the book Urine Proteomics in Kidney Disease Biomarker Discovery by , Springer Netherlands
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Author: ISBN: 9789401795234
Publisher: Springer Netherlands Publication: October 29, 2014
Imprint: Springer Language: English
Author:
ISBN: 9789401795234
Publisher: Springer Netherlands
Publication: October 29, 2014
Imprint: Springer
Language: English

This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the potential opportunities and risks in their study design. Kidney diseases are emphasized as they produce the most significant changes in urine. This book tries to show researchers and graduate students, who are in or entering the field, "all things considered" rather than "the current affair".

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This book systematically summarizes the ideas and technologies used in urine proteome analysis. It argues that change is the core of biomarker definition since the body uses its homeostatic mechanisms to correct changes in the blood. This means that urine is probably a better source of biomarkers than blood. A roadmap to the urinary biomarker era is proposed, and researchers are reminded of the potential opportunities and risks in their study design. Kidney diseases are emphasized as they produce the most significant changes in urine. This book tries to show researchers and graduate students, who are in or entering the field, "all things considered" rather than "the current affair".

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