Translational Biology in Medicine

Nonfiction, Health & Well Being, Medical, Medical Science, Biotechnology, Science & Nature, Science, Other Sciences, Molecular Biology
Cover of the book Translational Biology in Medicine by M. Montano, Elsevier Science
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Author: M. Montano ISBN: 9781908818652
Publisher: Elsevier Science Publication: December 8, 2014
Imprint: Woodhead Publishing Language: English
Author: M. Montano
ISBN: 9781908818652
Publisher: Elsevier Science
Publication: December 8, 2014
Imprint: Woodhead Publishing
Language: English

The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental model systems for disease, such as cell lines, primary cells, stem cells and animal models for disease, followed by a systematic description of genetic and genomic profiling and biomarker validation currently used in biomedical research. Examples of translation studies that have used these models and methods are presented, including studies in aging, tissue repair and chronic infection, each with an emphasis on how personalized medicine is transforming biomedicine. Bioethical considerations in translational study design and bioethical considerations in biomedical research are then covered, before concluding remarks, and a look towards the future of personalized medicine.

  • Describes cellular and animal model systems used in translational research
  • Discusses the use of blood, genetic and genomic biomarkers for disease
  • Presents translational studies in aging, tissue repair and infectious disease biomedicine
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The recent emphasis in biomedical research on translational biology and personalized medicine is revolutionizing conceptual and experimental approaches to understanding and improving human health. Translational Biology in Medicine begins with an introduction to experimental model systems for disease, such as cell lines, primary cells, stem cells and animal models for disease, followed by a systematic description of genetic and genomic profiling and biomarker validation currently used in biomedical research. Examples of translation studies that have used these models and methods are presented, including studies in aging, tissue repair and chronic infection, each with an emphasis on how personalized medicine is transforming biomedicine. Bioethical considerations in translational study design and bioethical considerations in biomedical research are then covered, before concluding remarks, and a look towards the future of personalized medicine.

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