Toxicity and Autophagy in Neurodegenerative Disorders

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Neuroscience, Neurology
Cover of the book Toxicity and Autophagy in Neurodegenerative Disorders by , Springer International Publishing
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Author: ISBN: 9783319139395
Publisher: Springer International Publishing Publication: May 4, 2015
Imprint: Springer Language: English
Author:
ISBN: 9783319139395
Publisher: Springer International Publishing
Publication: May 4, 2015
Imprint: Springer
Language: English

Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.

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Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.

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