Therapeutic Antibody Engineering

Current and Future Advances Driving the Strongest Growth Area in the Pharmaceutical Industry

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Science & Nature, Science, Biological Sciences, Biotechnology, Technology
Cover of the book Therapeutic Antibody Engineering by William R Strohl, Lila M Strohl, Elsevier Science
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: William R Strohl, Lila M Strohl ISBN: 9781908818096
Publisher: Elsevier Science Publication: October 16, 2012
Imprint: Woodhead Publishing Language: English
Author: William R Strohl, Lila M Strohl
ISBN: 9781908818096
Publisher: Elsevier Science
Publication: October 16, 2012
Imprint: Woodhead Publishing
Language: English

The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering.

  • Goes beyond the standard engineering issues covered by most books and delves into structure-function relationships
  • Integration of knowledge across all areas of antibody engineering, development, and marketing
  • Discusses how current and future genetic engineering of cell lines will pave the way for much higher productivity
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The field of antibody engineering has become a vital and integral part of making new, improved next generation therapeutic monoclonal antibodies, of which there are currently more than 300 in clinical trials across several therapeutic areas. Therapeutic antibody engineering examines all aspects of engineering monoclonal antibodies and analyses the effect that various genetic engineering approaches will have on future candidates. Chapters in the first part of the book provide an introduction to monoclonal antibodies, their discovery and development and the fundamental technologies used in their production. Following chapters cover a number of specific issues relating to different aspects of antibody engineering, including variable chain engineering, targets and mechanisms of action, classes of antibody and the use of antibody fragments, among many other topics. The last part of the book examines development issues, the interaction of human IgGs with non-human systems, and cell line development, before a conclusion looking at future issues affecting the field of therapeutic antibody engineering.

More books from Elsevier Science

Cover of the book Front-Line Librarianship by William R Strohl, Lila M Strohl
Cover of the book Multifunction Peripherals for PCs by William R Strohl, Lila M Strohl
Cover of the book Advances in Imaging and Electron Physics by William R Strohl, Lila M Strohl
Cover of the book New Trends in Genetic Risk Assessment by William R Strohl, Lila M Strohl
Cover of the book Granular Geomechanics by William R Strohl, Lila M Strohl
Cover of the book Permo-Triassic Salt Provinces of Europe, North Africa and the Atlantic Margins by William R Strohl, Lila M Strohl
Cover of the book Neuroanatomy for Medical Students by William R Strohl, Lila M Strohl
Cover of the book Basement Membranes by William R Strohl, Lila M Strohl
Cover of the book Optical Switches by William R Strohl, Lila M Strohl
Cover of the book The Tribology Handbook by William R Strohl, Lila M Strohl
Cover of the book Advances in Agronomy by William R Strohl, Lila M Strohl
Cover of the book Emotion Measurement by William R Strohl, Lila M Strohl
Cover of the book Scaling Chemical Processes by William R Strohl, Lila M Strohl
Cover of the book Control of Human Parasitic Diseases by William R Strohl, Lila M Strohl
Cover of the book Neurobiology of Social Behavior by William R Strohl, Lila M Strohl
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy