The Molecular and Cellular Basis of Neurodegenerative Diseases

Underlying Mechanisms

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Neuroscience, Science & Nature, Science, Biological Sciences
Cover of the book The Molecular and Cellular Basis of Neurodegenerative Diseases by , Elsevier Science
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Author: ISBN: 9780128113059
Publisher: Elsevier Science Publication: March 29, 2018
Imprint: Academic Press Language: English
Author:
ISBN: 9780128113059
Publisher: Elsevier Science
Publication: March 29, 2018
Imprint: Academic Press
Language: English

The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common.

This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field.

  • Covers the spectrum of neurodegenerative diseases and their complex genetic, pathological, biochemical and cellular features
  • Focuses on leading hypotheses regarding the biochemical and cellular dysfunctions that cause neurodegeneration
  • Details features, advantages and limitations of animal models, as well as prospects for therapeutic development
  • Authored by internationally recognized leaders in the field
  • Includes illustrations that help clarify and consolidate complex concepts
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The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common.

This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field.

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