Synthetic Analgesics
Morphinans: Benzomorphans
Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
| Author: | J. Hellerbach, O. Schnider, H. Besendorf | ISBN: | 9781483156286 |
| Publisher: | Elsevier Science | Publication: | April 24, 2014 |
| Imprint: | Pergamon | Language: | English |
| Author: | J. Hellerbach, O. Schnider, H. Besendorf |
| ISBN: | 9781483156286 |
| Publisher: | Elsevier Science |
| Publication: | April 24, 2014 |
| Imprint: | Pergamon |
| Language: | English |
Synthetic Analgesics provides a comprehensive discussion of morphinans and 6,7-benzomorphans. Morphinans belong to a class of compounds possessing the main structural skeleton of morphine. Chemists have attempted to modify the morphine molecule in order to obtain analgesics without side-effects and addictive properties. The book is organized into two parts. Part A discusses the chemistry and pharmacology of morphinans, covering the syntheses of analgesics with morphine-like activity, N-methyl-morphinan, 3-hydroxy-N-methyl-morphinan and analogous compounds, toxicity and analgesic action of morphinan, and morphinans with anti-morphine activity. Part B deals with the chemistry and pharmacology of 6,7-benzomorphans; and opiate antagonists in the benzomorphan series.
Synthetic Analgesics provides a comprehensive discussion of morphinans and 6,7-benzomorphans. Morphinans belong to a class of compounds possessing the main structural skeleton of morphine. Chemists have attempted to modify the morphine molecule in order to obtain analgesics without side-effects and addictive properties. The book is organized into two parts. Part A discusses the chemistry and pharmacology of morphinans, covering the syntheses of analgesics with morphine-like activity, N-methyl-morphinan, 3-hydroxy-N-methyl-morphinan and analogous compounds, toxicity and analgesic action of morphinan, and morphinans with anti-morphine activity. Part B deals with the chemistry and pharmacology of 6,7-benzomorphans; and opiate antagonists in the benzomorphan series.
