Protein Therapeutics

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
Cover of the book Protein Therapeutics by Raimund Mannhold, Gerd Folkers, Helmut Buschmann, Wiley
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Author: Raimund Mannhold, Gerd Folkers, Helmut Buschmann ISBN: 9783527699148
Publisher: Wiley Publication: August 2, 2017
Imprint: Wiley-VCH Language: English
Author: Raimund Mannhold, Gerd Folkers, Helmut Buschmann
ISBN: 9783527699148
Publisher: Wiley
Publication: August 2, 2017
Imprint: Wiley-VCH
Language: English

In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades.
Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

In this practice-oriented two volume handbook, professionals from some of the largest biopharmaceutical companies and top academic researchers address the key concepts and challenges in the development of protein pharmaceuticals for medicinal chemists and drug developers of all trades.
Following an introduction tracing the rapid development of the protein therapeutics market over the last decade, all currently used therapeutic protein scaffolds are surveyed, from human and non-human antibodies to antibody mimetics, bispecific antibodies and antibody-drug conjugates. This ready reference then goes on to review other key aspects such as pharmacokinetics, safety and immunogenicity, manufacture, formulation and delivery. The handbook then takes a look at current key clinical applications for protein therapeutics, from respiratory and inflammation to oncology and immune-oncology, infectious diseases and rescue therapy. Finally, several exciting prospects for the future of protein therapeutics are highlighted and discussed.

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