Prodrugs and Targeted Delivery
Towards Better ADME Properties
Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology
| Author: | Raimund Mannhold, Hugo Kubinyi, Gerd Folkers | ISBN: | 9783527633180 |
| Publisher: | Wiley | Publication: | January 11, 2011 |
| Imprint: | Wiley-VCH | Language: | English |
| Author: | Raimund Mannhold, Hugo Kubinyi, Gerd Folkers |
| ISBN: | 9783527633180 |
| Publisher: | Wiley |
| Publication: | January 11, 2011 |
| Imprint: | Wiley-VCH |
| Language: | English |
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs.
Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.
This topical reference and handbook addresses the chemistry, pharmacology, toxicology and the patentability of prodrugs, perfectly mirroring the integrated approach prevalent in today's drug design. It summarizes current experiences and strategies for the rational design of prodrugs, beginning at the early stages of the development process, as well as discussing organ- and site-selective prodrugs.
Every company employing medicinal chemists will be interested in this practice-oriented overview of a key strategy in modern drug discovery and development.
