Patient Derived Tumor Xenograft Models

Promise, Potential and Practice

Nonfiction, Health & Well Being, Medical, Veterinary Medicine, Surgery
Cover of the book Patient Derived Tumor Xenograft Models by , Elsevier Science
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Author: ISBN: 9780128040614
Publisher: Elsevier Science Publication: October 13, 2016
Imprint: Academic Press Language: English
Author:
ISBN: 9780128040614
Publisher: Elsevier Science
Publication: October 13, 2016
Imprint: Academic Press
Language: English

Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains.

In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory.

  • Offers guidance on data interpretation and regulatory aspects
  • Provides useful techniques and strategies for working with PDX models
  • Includes practical tools and potential pitfalls for best practices
  • Compiles all knowledge of PDX models research in one resource
  • Presents the results of first ever global survey on standards of PDX development and usage in academia and industry
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Patient Derived Tumor Xenograft Models: Promise, Potential and Practice offers guidance on how to conduct PDX modeling and trials, including how to know when these models are appropriate for use, and how the data should be interpreted through the selection of immunodeficient strains.

In addition, proper methodologies suitable for growing different type of tumors, acquisition of pathology, genomic and other data about the tumor, potential pitfalls, and confounding background pathologies that occur in these models are also included, as is a discussion of the facilities and infrastructure required to operate a PDX laboratory.

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