Neonatal Hyperbilirubinemia in Preterm Neonates, An Issue of Clinics in Perinatology, E-Book

Nonfiction, Health & Well Being, Medical, Specialties, Perinatology & Neonatology, Gynecology & Obstetrics
Cover of the book Neonatal Hyperbilirubinemia in Preterm Neonates, An Issue of Clinics in Perinatology, E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP, Elsevier Health Sciences
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP ISBN: 9780323446297
Publisher: Elsevier Health Sciences Publication: June 10, 2016
Imprint: Elsevier Language: English
Author: David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
ISBN: 9780323446297
Publisher: Elsevier Health Sciences
Publication: June 10, 2016
Imprint: Elsevier
Language: English

Preterm neonates remain at increased risk for adverse bilirubin-related outcomes, including acute bilirubin encephalopathy relative to term infants. Yet, most vulnerable neonates are likely to benefit from the potent anti-oxidant properties of bilirubin. Evidence-based guidelines for the management of hyperbilirubinemia in preterm infants, however, are lacking. High concentrations of unconjugated bilirubin can cause permanent neurologic damage in infants, evident through magnetic resonance imaging of chronic bilirubin encephalopathy or kernicterus. There is a growing concern that exposures to even moderate concentrations of bilirubin may lead to subtle but permanent neurodevelopmental impairment referred to as bilirubin-induced neurologic dysfunction. Our current use of phototherapy to decrease bilirubin loads and its potential photo-oxidant properties is a biological conundrum that has been questioned in the use of phototherapy for very low birth weight neonates. In this issue of Clinics in Perinatology, we provide updates on the current understanding of the biology, mechanisms of increasing bilirubin load due to hemolysis, decreased bilirubin binding capacity and glucose-6-phosphate dehydrogenase deficiency, as well as clinical strategies to operationalize the thresholds for hyperbilirubinemia interventions in preterm infants.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Preterm neonates remain at increased risk for adverse bilirubin-related outcomes, including acute bilirubin encephalopathy relative to term infants. Yet, most vulnerable neonates are likely to benefit from the potent anti-oxidant properties of bilirubin. Evidence-based guidelines for the management of hyperbilirubinemia in preterm infants, however, are lacking. High concentrations of unconjugated bilirubin can cause permanent neurologic damage in infants, evident through magnetic resonance imaging of chronic bilirubin encephalopathy or kernicterus. There is a growing concern that exposures to even moderate concentrations of bilirubin may lead to subtle but permanent neurodevelopmental impairment referred to as bilirubin-induced neurologic dysfunction. Our current use of phototherapy to decrease bilirubin loads and its potential photo-oxidant properties is a biological conundrum that has been questioned in the use of phototherapy for very low birth weight neonates. In this issue of Clinics in Perinatology, we provide updates on the current understanding of the biology, mechanisms of increasing bilirubin load due to hemolysis, decreased bilirubin binding capacity and glucose-6-phosphate dehydrogenase deficiency, as well as clinical strategies to operationalize the thresholds for hyperbilirubinemia interventions in preterm infants.

More books from Elsevier Health Sciences

Cover of the book IASLC Thoracic Oncology E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Frührehabilitation in der Intensivmedizin by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Communication by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Chest X-Ray Made Easy E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Diagnosis, Management, and Treatment of Discogenic Pain E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Dental Clinical Advisor - E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book AANA Advanced Arthroscopy: The Foot and Ankle E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Fetal Monitoring in Practice E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book PflegeWissen, Aktivierung und Beschäftigung by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Sturdevant's Art & Science of Operative Dentistry - E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Craniomaxillofacial Trauma, An Issue of Atlas of the Oral and Maxillofacial Surgery Clinics, by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Merrill's Atlas of Radiographic Positioning and Procedures - E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Neuromuscular Disease Management and Rehabilitation, Part II: Specialty Care and Therapeutics, an Issue of Physical Medicine and Rehabilitation Clinics, E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Foot and Ankle Innovations in Latin America, An Issue of Foot and Ankle Clinics - E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
Cover of the book Bovine Clinical Pharmacology, An Issue of Veterinary Clinics of North America: Food Animal Practice, E-Book by David K. Stevenson, MD, Vinod K. Bhutani, MD, FAAP
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy