Methods in Research and Development of Biomedical Devices

This book presents a road map for applying the stages in conceptualization, evaluation, and testing of biomedical devices in a systematic order of approach, leading to solutions for medical problems within a well-deserved safety limit. The issues discussed will pave the way for understanding the preliminary concepts used in modern biomedical device engineering, which include medical imaging, computational fluid dynamics, finite element analysis, particle image velocimetry, and rapid prototyping. This book would undoubtedly be of use to biomedical engineers, medical doctors, radiologists, and any other professionals related to the research and development of devices for health care.

Contents:

• Introduction
• Overview of Biomedical Technologies
• Conceptualisation and Medical Image-Based Modelling
• Medical Imaging and Visualisation
• Treatment of Aneurysms
• Endovascular Stent Grafts
• Nasal Drug Delivery
• Biomedical MEMS Micropump
• Engineering and Production Management for Biomedical Devices

Readership: Engineers, doctors and students in the biomedical and biomechanical engineering, and radiology fields.
Key Features:

• We outline the development of a biomedical device or a medical-assisting mechanism, which involves the system integration of various modelling, evaluation, or testing components to lead to the successful examination of a product that meets the medical application safety threshold
• The system of analysing the testing and development of biomedical devices is also presented. It exists to facilitate a smooth flow of implementations that evaluate medical implants and mechanisms in order to meet the desired reliability and safety levels. The introduction of advanced modelling and testing procedures for the accurate evaluation of devices, as well as the capability of the system to identify and quantify flow behaviour through it can result in clinically safe designs and give medical experts a leading edge in saving patients
• We focus on the characteristics of modelling and evaluation of heart valve implants, stents, stent grafts, and drug delivery mechanisms to illustrate the instruments used in testing these cardiac or respiratory flow-related biomedical applications
• We introduce the fundamental concepts of computational fluid dynamics (CFD) and finite element analysis (FEA) with applications onto some selected biomedical devices as well as highlight the nature of their applications and impact to the medical industry
• Computational tools such as computer-aided design (CAD) software and numerical solvers for CFD, as well as flow visualisation packages, which are mainly used in simulation, visualisation, and verification stages of the development are listed in appendices
• This book contributes the framework behind the implementation of biomedical devices and applications in the systematic format, and describes the key instruments used in their development. Experimental and clinical verification listed in detail here will complement the existing computational results based on the device performance and vice versa