Leucocyte Trafficking

The Role of Fucosyltransferases and Selectins

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Physiology
Cover of the book Leucocyte Trafficking by , Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783662053973
Publisher: Springer Berlin Heidelberg Publication: June 29, 2013
Imprint: Springer Language: English
Author:
ISBN: 9783662053973
Publisher: Springer Berlin Heidelberg
Publication: June 29, 2013
Imprint: Springer
Language: English

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

More books from Springer Berlin Heidelberg

Cover of the book Ecological Perception Research, Visual Communication, and Aesthetics by
Cover of the book Grundkurs Theoretische Physik 3 by
Cover of the book The Use of Smart Mobile Equipment for the Innovation in Organizational Coordination by
Cover of the book Das Urinsediment by
Cover of the book Gesprächsführung in technischen Berufen by
Cover of the book Investigations on Mesoscale Structure in Gas–Solid Fluidization and Heterogeneous Drag Model by
Cover of the book Mastopexy and Breast Reduction by
Cover of the book Basement Regions by
Cover of the book Balances by
Cover of the book Environmental Geophysics by
Cover of the book IT-Services in der Cloud und ISAE 3402 by
Cover of the book Open Learning Cultures by
Cover of the book Annual Review of Gerontology and Geriatrics by
Cover of the book Brachial Plexus Lesions by
Cover of the book PNF in Practice by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy