Insertional Mutagenesis Strategies in Cancer Genetics

Nonfiction, Health & Well Being, Medical, Medical Science, Genetics, Specialties, Oncology
Cover of the book Insertional Mutagenesis Strategies in Cancer Genetics by , Springer New York
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Author: ISBN: 9781441976567
Publisher: Springer New York Publication: November 18, 2010
Imprint: Springer Language: English
Author:
ISBN: 9781441976567
Publisher: Springer New York
Publication: November 18, 2010
Imprint: Springer
Language: English

The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.

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The goal of this work is summarize the contribution that insertional mutagenesis has made to our understanding of cancer. A variety of insertional mutagens are presented that have been used to study a variety of tumor types in several model organisms. In addition, the impact of insertional mutagenesis in several gene therapy trials is discussed along with strategies to avoid such complications in future clinical trials.

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