Inflammation and Lung Cancer

Nonfiction, Health & Well Being, Medical, Specialties, Pathology, Oncology
Cover of the book Inflammation and Lung Cancer by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781493927241
Publisher: Springer New York Publication: June 24, 2015
Imprint: Springer Language: English
Author:
ISBN: 9781493927241
Publisher: Springer New York
Publication: June 24, 2015
Imprint: Springer
Language: English

In recent years there have been various discoveries connecting inflammation and lung cancer and clearly there is growing interest in this area of cancer research. The link between unresolved inflammation and cancer has been well established with estimates that 15% of cancer deaths are inflammation‐related. Evidence for this link includes the following: a) some inflammatory diseases are associated with increased risk of cancer development; b) inflammatory mediators are present surrounding and within most tumors; c) overexpression of inflammatory cytokines increases cancer development and progression in murine studies; d) inhibition of inflammatory mediators decreases cancer development and progression; and e) the use of non‐steroidal anti‐inflammatory drugs (NSAIDs) has been found to decrease cancer incidence and delay progression. The volume will present aspects of the inflammatory tumor microenvironment (TME), its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of micro‐RNAs (miRNAs) and an increase in a stem cell phenotype. The book will also cover the mechanisms of inflammatory mediators. Chronic overexpression of inflammatory mediators in the TME, as seen in smokers and patients with non‐small cell lung cancer (NSCLC), can also lead to increased tumor initiation, progression, invasion and metastasis. The volume will provide a comprehensive perspective of the latest findings and summaries of progress made regarding inflammation and its connection to lung cancer.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

In recent years there have been various discoveries connecting inflammation and lung cancer and clearly there is growing interest in this area of cancer research. The link between unresolved inflammation and cancer has been well established with estimates that 15% of cancer deaths are inflammation‐related. Evidence for this link includes the following: a) some inflammatory diseases are associated with increased risk of cancer development; b) inflammatory mediators are present surrounding and within most tumors; c) overexpression of inflammatory cytokines increases cancer development and progression in murine studies; d) inhibition of inflammatory mediators decreases cancer development and progression; and e) the use of non‐steroidal anti‐inflammatory drugs (NSAIDs) has been found to decrease cancer incidence and delay progression. The volume will present aspects of the inflammatory tumor microenvironment (TME), its many roles in tumor progression and metastasis, including creation of a hypoxic environment, increased angiogenesis and invasion, changes in expression of micro‐RNAs (miRNAs) and an increase in a stem cell phenotype. The book will also cover the mechanisms of inflammatory mediators. Chronic overexpression of inflammatory mediators in the TME, as seen in smokers and patients with non‐small cell lung cancer (NSCLC), can also lead to increased tumor initiation, progression, invasion and metastasis. The volume will provide a comprehensive perspective of the latest findings and summaries of progress made regarding inflammation and its connection to lung cancer.

More books from Springer New York

Cover of the book Common Neurosurgical Conditions in the Pediatric Practice by
Cover of the book The Arc of Life by
Cover of the book Reviews of Environmental Contamination and Toxicology by
Cover of the book Living with Water by
Cover of the book Multiprocessor Systems on Chip by
Cover of the book Synthesis of Computational Structures for Analog Signal Processing by
Cover of the book Fashion Branding and Consumer Behaviors by
Cover of the book Hyperspectral Image Fusion by
Cover of the book Ovarian Cell Interactions by
Cover of the book Computational Biology by
Cover of the book Language and Social Situations by
Cover of the book Stability and Transport in Magnetic Confinement Systems by
Cover of the book Search for the Ultimate Energy Source by
Cover of the book Calabi-Yau Varieties: Arithmetic, Geometry and Physics by
Cover of the book Mathematical Statistics for Economics and Business by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy