Induced Pluripotent Stem Cells in Brain Diseases

Understanding the Methods, Epigenetic Basis, and Applications for Regenerative Medicine.

Nonfiction, Science & Nature, Science, Biological Sciences, Cytology, Health & Well Being, Medical, Specialties, Internal Medicine, Neurology
Cover of the book Induced Pluripotent Stem Cells in Brain Diseases by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner, Springer Netherlands
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner ISBN: 9789400728165
Publisher: Springer Netherlands Publication: November 23, 2011
Imprint: Springer Language: English
Author: Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
ISBN: 9789400728165
Publisher: Springer Netherlands
Publication: November 23, 2011
Imprint: Springer
Language: English

Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug treatment screening. However, this method faces issues of low reprogramming efficiency, and poorly defined criteria for determining the conversion of one cell type to another. Cells contain epigenetic “memories” of what they were that can affect reprogramming. This book discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson’s disease and Vanishing White Matter (VWM).​

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Brain diseases can have a large impact on patients and society, and treatment is often not available. A new approach in which somatic cells are reprogrammed into induced pluripotent cells (iPS cells) is a significant breakthrough for regenerative medicine. This promises patient-specific tissue for replacement therapies, as well as disease-specific cells for developmental modeling and drug treatment screening. However, this method faces issues of low reprogramming efficiency, and poorly defined criteria for determining the conversion of one cell type to another. Cells contain epigenetic “memories” of what they were that can affect reprogramming. This book discusses the various methods to reprogram cells, the control and determination of cell identity, the epigenetic models that have emerged and the application of iPS cell therapy for brain diseases, in particular Parkinson’s disease and Vanishing White Matter (VWM).​

More books from Springer Netherlands

Cover of the book Stem Cell Biology in Health and Disease by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Practicing Professional Ethics in Economics and Public Policy by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book The Treatment of Renal Failure by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Mobile Media, Political Participation, and Civic Activism in Asia by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Mental Well-Being by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Legal and Ethical Concerns in Treating Kidney Failure by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Hierarchy and the Definition of Order in the Letters of Pseudo-Dionysius by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Psychiatry as Medicine by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Modulation of Presynaptic Calcium Channels by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Lake Issyk-Kul: Its Natural Environment by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Stem Cells and Human Diseases by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Theory and Applications of Smart Cameras by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Model Systems to Study the Excretory Function of Higher Plants by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Quality of life in Italy by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
Cover of the book Nature Across Cultures by Vivi M. Heine, Stephanie Dooves, Dwayne Holmes, Judith Wagner
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy