Genomics of Pattern Recognition Receptors
Applications in Oncology and Cardiovascular Diseases
Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Science & Nature, Science, Biological Sciences, Biochemistry
| Author: | Anton G. Kutikhin, Arseniy E. Yuzhalin | ISBN: | 9783034806886 |
| Publisher: | Springer Basel | Publication: | August 28, 2013 |
| Imprint: | Springer | Language: | English |
| Author: | Anton G. Kutikhin, Arseniy E. Yuzhalin |
| ISBN: | 9783034806886 |
| Publisher: | Springer Basel |
| Publication: | August 28, 2013 |
| Imprint: | Springer |
| Language: | English |
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
This book offers comprehensive information on the polymorphisms of genes encoding pattern recognition receptors (PRRs). Following a short description of the general role of PRRs in the immune system, the structure and function of Toll-like and NOD-like receptors are examined in detail. The main focus is on the role of inherited variation in PRRs and their correlation to cancer and cardiovascular diseases. A review of all epidemiological investigations is included, and a concept of genomic risk markers for the prevention of various diseases is also discussed.
