Genetic Susceptibility to Cancer

Nonfiction, Health & Well Being, Medical, Specialties, Oncology, Veterinary Medicine
Cover of the book Genetic Susceptibility to Cancer by Seymour Garte, Springer US
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: Seymour Garte ISBN: 9781461549895
Publisher: Springer US Publication: March 9, 2013
Imprint: Springer Language: English
Author: Seymour Garte
ISBN: 9781461549895
Publisher: Springer US
Publication: March 9, 2013
Imprint: Springer
Language: English

Despite recent progress in many areas of treatment and control, cancer remains a frightening threat to everyone. While scientists have known for decades that the majority of human cancers are caused by environmental agents such as radiation and the chemicals in cigarette smoke, not everyone who smokes gets lung cancer. Furthermore, many people who assiduously avoid all possible risk from smoking, diet, and pollution still succumb to some form of cancer later in life. Does this mean that there is an element of blind chance in the underlying mechanisms of human carcinogenesis? To what extent do genetic influences play a role in determining the cancer risk of individuals?
A number of `cancer families', in which several closely related individuals have suffered from various specific forms of cancer, have been studied by genetic epidemiologists. However, for the majority of cancer cases, little or no discernible genetic influence or family history is found. Recent research has discovered that for many of these `sporadic' (non-familial) cancer cases, defects or aberrations in certain metabolic genes not previously associated with genetic cancer risk may contribute to either causing the disease or at least increasing the chances of developing cancer. It is therefore possible that much of what has previously passed for `bad luck' may turn out to be a new type of `bad genes'.
Genetic Susceptibility to Cancer explains that this new idea of `bad genes' may contain an unexpected positive side. The carcinogenic effects of these metabolic genes, unlike those of the oncogenes and tumor suppressor genes that are responsible for the inherited cancer syndromes, can potentially be overcome or nullified.
Genetic Susceptibility to Cancer will provide a valuable reference for health professionals, researchers, clinicians and biomedical scientists who are interested in the current thinking in this critically important area of cancer management.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Despite recent progress in many areas of treatment and control, cancer remains a frightening threat to everyone. While scientists have known for decades that the majority of human cancers are caused by environmental agents such as radiation and the chemicals in cigarette smoke, not everyone who smokes gets lung cancer. Furthermore, many people who assiduously avoid all possible risk from smoking, diet, and pollution still succumb to some form of cancer later in life. Does this mean that there is an element of blind chance in the underlying mechanisms of human carcinogenesis? To what extent do genetic influences play a role in determining the cancer risk of individuals?
A number of `cancer families', in which several closely related individuals have suffered from various specific forms of cancer, have been studied by genetic epidemiologists. However, for the majority of cancer cases, little or no discernible genetic influence or family history is found. Recent research has discovered that for many of these `sporadic' (non-familial) cancer cases, defects or aberrations in certain metabolic genes not previously associated with genetic cancer risk may contribute to either causing the disease or at least increasing the chances of developing cancer. It is therefore possible that much of what has previously passed for `bad luck' may turn out to be a new type of `bad genes'.
Genetic Susceptibility to Cancer explains that this new idea of `bad genes' may contain an unexpected positive side. The carcinogenic effects of these metabolic genes, unlike those of the oncogenes and tumor suppressor genes that are responsible for the inherited cancer syndromes, can potentially be overcome or nullified.
Genetic Susceptibility to Cancer will provide a valuable reference for health professionals, researchers, clinicians and biomedical scientists who are interested in the current thinking in this critically important area of cancer management.

More books from Springer US

Cover of the book Cardiovascular Drug Therapy in the Elderly by Seymour Garte
Cover of the book Sexuality by Seymour Garte
Cover of the book Vaccine Design by Seymour Garte
Cover of the book Encyclopedia of Prehistory by Seymour Garte
Cover of the book WIG Craft and Ekranoplan by Seymour Garte
Cover of the book Risk Analysis of Complex and Uncertain Systems by Seymour Garte
Cover of the book Handbook of Psychopharmacology by Seymour Garte
Cover of the book Monitoring the Quality of Health Care by Seymour Garte
Cover of the book Calcium-Sensing Receptor by Seymour Garte
Cover of the book The Gangliosidoses by Seymour Garte
Cover of the book Formal Development of a Network-Centric RTOS by Seymour Garte
Cover of the book Ecotones by Seymour Garte
Cover of the book Are Small Firms Important? Their Role and Impact by Seymour Garte
Cover of the book Clinical Investigation of the Microcirculation by Seymour Garte
Cover of the book Tree Fruit Production by Seymour Garte
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy