Fibrinolytic Bacterial Enzymes with Thrombolytic Activity

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Hematology, Medical Science, Microbiology
Cover of the book Fibrinolytic Bacterial Enzymes with Thrombolytic Activity by Essam Kotb, Springer Berlin Heidelberg
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Author: Essam Kotb ISBN: 9783642249808
Publisher: Springer Berlin Heidelberg Publication: January 4, 2012
Imprint: Springer Language: English
Author: Essam Kotb
ISBN: 9783642249808
Publisher: Springer Berlin Heidelberg
Publication: January 4, 2012
Imprint: Springer
Language: English

Stress, high blood pressure, smoking, pollution, fast foods, overweight, excessive travelling, surgery, less movement are common features in our modern life. These features are risky for blood clotting disorders. According to WHO, over 29% of the total mortalities worldwide are due to thrombosis. By the year, 2020 cardiovascular diseases (CVDs) may cause an estimated 25 million deaths per year, thus antithrombotic therapy is of great interest.

The available thrombolytic agents such as urokinase are highly expensive, antigenic, quite unspecific, pyretogenic and hemorrhagenic. Therefore, the production of fibrinolysing enzymes, which rapidly dissolute thrombi within the vascular tree, without the detriments by microorganisms, as described in this book, is the desirable aim of today’s research.

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Stress, high blood pressure, smoking, pollution, fast foods, overweight, excessive travelling, surgery, less movement are common features in our modern life. These features are risky for blood clotting disorders. According to WHO, over 29% of the total mortalities worldwide are due to thrombosis. By the year, 2020 cardiovascular diseases (CVDs) may cause an estimated 25 million deaths per year, thus antithrombotic therapy is of great interest.

The available thrombolytic agents such as urokinase are highly expensive, antigenic, quite unspecific, pyretogenic and hemorrhagenic. Therefore, the production of fibrinolysing enzymes, which rapidly dissolute thrombi within the vascular tree, without the detriments by microorganisms, as described in this book, is the desirable aim of today’s research.

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