Epigenetics and Neuroplasticity - Evidence and Debate

Nonfiction, Science & Nature, Science, Biological Sciences, Genetics
Cover of the book Epigenetics and Neuroplasticity - Evidence and Debate by Schahram Akbarian, Farah Lubin, Elsevier Science
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Author: Schahram Akbarian, Farah Lubin ISBN: 9780128010853
Publisher: Elsevier Science Publication: November 5, 2014
Imprint: Academic Press Language: English
Author: Schahram Akbarian, Farah Lubin
ISBN: 9780128010853
Publisher: Elsevier Science
Publication: November 5, 2014
Imprint: Academic Press
Language: English

The ‘epi-(Greek for ‘over’, ‘above’)genome’, with its rich cache of highly regulated, structural modifications—including DNA methylation, histone modifications and histone variants—defines the moldings and three-dimensional structures of the genomic material inside the cell nucleus and serves, literally, as a molecular bridge linking the environment to the genetic materials in our brain cells. Due to technological and scientific advances in the field, the field of neuroepigenetics is currently one of the hottest topics in the basic and clinical neurosciences. The volume captures some of this vibrant and exciting new research, and conveys to the reader an up-to-date discussion on the role of epigenetics across the lifespan of the human brain in health and disease.

  • Topics cover the entire lifespan of the brain, from transgenerational epigenetics to neurodevelopmental disease to disorders of the aging brain.
  • All chapters are written with dual intent, to provide the reader with a timely update on the field, and a discussion of provocative or controversial findings in the field with the potential of great impact for future developments in the field.
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The ‘epi-(Greek for ‘over’, ‘above’)genome’, with its rich cache of highly regulated, structural modifications—including DNA methylation, histone modifications and histone variants—defines the moldings and three-dimensional structures of the genomic material inside the cell nucleus and serves, literally, as a molecular bridge linking the environment to the genetic materials in our brain cells. Due to technological and scientific advances in the field, the field of neuroepigenetics is currently one of the hottest topics in the basic and clinical neurosciences. The volume captures some of this vibrant and exciting new research, and conveys to the reader an up-to-date discussion on the role of epigenetics across the lifespan of the human brain in health and disease.

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