Discovering and Developing Molecules with Optimal Drug-Like Properties

Nonfiction, Health & Well Being, Medical, Specialties, Pharmacy, Science & Nature, Technology, Engineering, Chemical & Biochemical
Cover of the book Discovering and Developing Molecules with Optimal Drug-Like Properties by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781493913992
Publisher: Springer New York Publication: October 31, 2014
Imprint: Springer Language: English
Author:
ISBN: 9781493913992
Publisher: Springer New York
Publication: October 31, 2014
Imprint: Springer
Language: English

This authoritative volume provides a contemporary view on the latest research in molecules with optimal drug-like properties. It is a valuable source to access current best practices as well as new research techniques and strategies. Written by leading scientists in their fields, the text consists of fourteen chapters with an underlying theme of early collaborative opportunities between pharmaceutical and discovery sciences. The book explores the practical realities of performing physical pharmaceutical and biopharmaceutical research in the context of drug discovery with short timelines and low compound availability. Chapters cover strategies and tactics to enable discovery as well as predictive approaches to establish, understand and communicate risks in early development. It also examines the detection, characterization, and assessment of risks on the solid state properties of advanced discovery and early development candidates, highlighting the link between solid state properties and critical development parameters such as solubility and stability. Final chapters center on techniques to improve molecular solubilization and prevent precipitation, with particularly emphasis on linking physiochemical properties of molecules to formulation selection in preclinical and clinical settings.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

This authoritative volume provides a contemporary view on the latest research in molecules with optimal drug-like properties. It is a valuable source to access current best practices as well as new research techniques and strategies. Written by leading scientists in their fields, the text consists of fourteen chapters with an underlying theme of early collaborative opportunities between pharmaceutical and discovery sciences. The book explores the practical realities of performing physical pharmaceutical and biopharmaceutical research in the context of drug discovery with short timelines and low compound availability. Chapters cover strategies and tactics to enable discovery as well as predictive approaches to establish, understand and communicate risks in early development. It also examines the detection, characterization, and assessment of risks on the solid state properties of advanced discovery and early development candidates, highlighting the link between solid state properties and critical development parameters such as solubility and stability. Final chapters center on techniques to improve molecular solubilization and prevent precipitation, with particularly emphasis on linking physiochemical properties of molecules to formulation selection in preclinical and clinical settings.

More books from Springer New York

Cover of the book Translational Stroke Research by
Cover of the book Archaeology in Society by
Cover of the book Digital Youth by
Cover of the book The Changing Business Landscape of Romania by
Cover of the book Conservation of Tropical Plant Species by
Cover of the book Sonocrystallization of Fats by
Cover of the book Resource Management for Multimedia Services in High Data Rate Wireless Networks by
Cover of the book Integrating Zooarchaeology and Paleoethnobotany by
Cover of the book Essential Elements for a GMP Analytical Chemistry Department by
Cover of the book Practical Urological Ultrasound by
Cover of the book Divergence Operator and Related Inequalities by
Cover of the book Biomedical Optics in Otorhinolaryngology by
Cover of the book Recent Trends in Theoretical Psychology by
Cover of the book Treatment of the Obese Patient by
Cover of the book A Clinical Information System for Oncology by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy