Complex Systems and Computational Biology Approaches to Acute Inflammation

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Science & Nature, Science, Biological Sciences
Cover of the book Complex Systems and Computational Biology Approaches to Acute Inflammation by , Springer New York
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781461480082
Publisher: Springer New York Publication: August 15, 2013
Imprint: Springer Language: English
Author:
ISBN: 9781461480082
Publisher: Springer New York
Publication: August 15, 2013
Imprint: Springer
Language: English

The difficulty in achieving effective translation of basic mechanistic biomedical knowledge into effective therapeutics, is the greatest challenge in biomedical research. Nowhere is this more apparent than in the reductionist approaches to understanding and manipulating the acute inflammatory response in the settings of sepsis, trauma/hemorrhage, wound healing, and related processes. This book discusses complex systems and computational biology methods and approaches that have advanced sufficiently to allow for knowledge generation, knowledge integration, and clinical translation in the settings of complex diseases related to the inflammatory response. Well-regulated, self-resolving inflammation is necessary for the appropriate communication and resolution of infection and trauma, and for maintenance of proper physiology and homeostasis. In contrast, self-sustaining inflammation drives the pathobiology of the aforementioned diseases. It is now increasingly recognized that controlling and reprogramming inflammation in order to reap the benefits of this evolutionarily-conserved process is preferred to simply abolishing indiscriminately.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

The difficulty in achieving effective translation of basic mechanistic biomedical knowledge into effective therapeutics, is the greatest challenge in biomedical research. Nowhere is this more apparent than in the reductionist approaches to understanding and manipulating the acute inflammatory response in the settings of sepsis, trauma/hemorrhage, wound healing, and related processes. This book discusses complex systems and computational biology methods and approaches that have advanced sufficiently to allow for knowledge generation, knowledge integration, and clinical translation in the settings of complex diseases related to the inflammatory response. Well-regulated, self-resolving inflammation is necessary for the appropriate communication and resolution of infection and trauma, and for maintenance of proper physiology and homeostasis. In contrast, self-sustaining inflammation drives the pathobiology of the aforementioned diseases. It is now increasingly recognized that controlling and reprogramming inflammation in order to reap the benefits of this evolutionarily-conserved process is preferred to simply abolishing indiscriminately.

More books from Springer New York

Cover of the book Aging 2000: Our Health Care Destiny by
Cover of the book Nonlinear Approaches in Engineering Applications 2 by
Cover of the book Stress Signaling in Plants: Genomics and Proteomics Perspective, Volume 1 by
Cover of the book Applied Inverse Problems by
Cover of the book Molecular Biophysics for the Life Sciences by
Cover of the book Neutral and Indifference Portfolio Pricing, Hedging and Investing by
Cover of the book Lecture Notes on the General Theory of Relativity by
Cover of the book Phenology of Ecosystem Processes by
Cover of the book Handbook of Community Sentiment by
Cover of the book Management of Headache and Headache Medications by
Cover of the book Elements of Marine Ecology by
Cover of the book An Introduction to Continuous-Time Stochastic Processes by
Cover of the book Arnold Sommerfeld by
Cover of the book CMOS IC Design for Wireless Medical and Health Care by
Cover of the book Performance Models and Risk Management in Communications Systems by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy