Chemical Biology of Glycoproteins

Nonfiction, Science & Nature, Science, Biological Sciences, Biochemistry, Chemistry, General Chemistry
Cover of the book Chemical Biology of Glycoproteins by Zhongping Tan, Lai-Xi Wang, Michael Boyce, Suwei Dong, Peng George Wang, Xuefei Huang, Robert J. Linhardt, Zhongwu Guo, Xing Chen, Max Crispin, Yan-Mei Li, Qun Zhou, Tom Brown, Royal Society of Chemistry
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Author: Zhongping Tan, Lai-Xi Wang, Michael Boyce, Suwei Dong, Peng George Wang, Xuefei Huang, Robert J. Linhardt, Zhongwu Guo, Xing Chen, Max Crispin, Yan-Mei Li, Qun Zhou, Tom Brown ISBN: 9781788011228
Publisher: Royal Society of Chemistry Publication: March 20, 2017
Imprint: Royal Society of Chemistry Language: English
Author: Zhongping Tan, Lai-Xi Wang, Michael Boyce, Suwei Dong, Peng George Wang, Xuefei Huang, Robert J. Linhardt, Zhongwu Guo, Xing Chen, Max Crispin, Yan-Mei Li, Qun Zhou, Tom Brown
ISBN: 9781788011228
Publisher: Royal Society of Chemistry
Publication: March 20, 2017
Imprint: Royal Society of Chemistry
Language: English

Glycans play a vital role in modulating protein structure and function from involvement in protein folding, solubility and stability to regulation of tissue distribution, recognition specificity, and biological activity. They can act as both positive and negative regulators of protein function, providing an additional level of control with respect to genetic and environmental conditions.

Due to the complexity of glycosylated protein forms, elucidating structural and functional information has been challenging task for researchers but recent development of chemical biology-based tools and techniques is bridging these knowledge gaps. This book provides a thorough review of the current state of glycoprotein chemical biology, describing the development and application of glycoprotein and glycan synthesis technologies for understanding and manipulating protein glycosylation.

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Glycans play a vital role in modulating protein structure and function from involvement in protein folding, solubility and stability to regulation of tissue distribution, recognition specificity, and biological activity. They can act as both positive and negative regulators of protein function, providing an additional level of control with respect to genetic and environmental conditions.

Due to the complexity of glycosylated protein forms, elucidating structural and functional information has been challenging task for researchers but recent development of chemical biology-based tools and techniques is bridging these knowledge gaps. This book provides a thorough review of the current state of glycoprotein chemical biology, describing the development and application of glycoprotein and glycan synthesis technologies for understanding and manipulating protein glycosylation.

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