Cardiovascular Safety in Drug Development and Therapeutic Use

New Methodologies and Evolving Regulatory Landscapes

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology, Specialties, Internal Medicine, Cardiology
Cover of the book Cardiovascular Safety in Drug Development and Therapeutic Use by J. Rick Turner, Dilip R. Karnad, Snehal Kothari, Springer International Publishing
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: J. Rick Turner, Dilip R. Karnad, Snehal Kothari ISBN: 9783319403472
Publisher: Springer International Publishing Publication: July 28, 2016
Imprint: Adis Language: English
Author: J. Rick Turner, Dilip R. Karnad, Snehal Kothari
ISBN: 9783319403472
Publisher: Springer International Publishing
Publication: July 28, 2016
Imprint: Adis
Language: English

At a time when the field of cardiac safety is going through important changes, this unique book provides the rationale for, and cutting-edge explanations of, new regulatory landscapes that will likely govern cardiac safety assessments globally for the foreseeable future.  Exposure-response modeling is already being accepted by regulatory agencies in lieu of the traditional Thorough QT/QTc Study, and the Comprehensive *in vitro *Proarrhythmia Assay initiative is well under way.

Developments in the field of cardiovascular safety are also described and discussed in the book.  These include the search for more efficient ways to exonerate new drugs for type 2 diabetes from an unacceptable cardiovascular liability, how best to address off-target blood pressure increases induced by noncardiovascular drugs, and the continued evolution of the discipline of Cardio-oncology.

“a resource that will likely serve as a standard for years to come” 

- Dr Jonathan Seltzer

Therapeutic Innovation & Regulatory Science, 2017;51(2):180

“I have no hesitation in recommending this book as a valuable reference source” 

- Dr Rashmi Shah

Journal for Clinical Studies, 2017;9(1):62-63

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

At a time when the field of cardiac safety is going through important changes, this unique book provides the rationale for, and cutting-edge explanations of, new regulatory landscapes that will likely govern cardiac safety assessments globally for the foreseeable future.  Exposure-response modeling is already being accepted by regulatory agencies in lieu of the traditional Thorough QT/QTc Study, and the Comprehensive *in vitro *Proarrhythmia Assay initiative is well under way.

Developments in the field of cardiovascular safety are also described and discussed in the book.  These include the search for more efficient ways to exonerate new drugs for type 2 diabetes from an unacceptable cardiovascular liability, how best to address off-target blood pressure increases induced by noncardiovascular drugs, and the continued evolution of the discipline of Cardio-oncology.

“a resource that will likely serve as a standard for years to come” 

- Dr Jonathan Seltzer

Therapeutic Innovation & Regulatory Science, 2017;51(2):180

“I have no hesitation in recommending this book as a valuable reference source” 

- Dr Rashmi Shah

Journal for Clinical Studies, 2017;9(1):62-63

More books from Springer International Publishing

Cover of the book Guide to Digital Forensics by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Science, Culture and the Search for Life on Other Worlds by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Modeling Cellular Systems by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Personalized Medicine in Healthcare Systems by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Endodontic Diagnosis, Pathology, and Treatment Planning by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Crowd-Powered Mobile Computing and Smart Things by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Improving Sustainability During Hospital Design and Operation by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Power Electronics for the Next Generation Wind Turbine System by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book The High Representative and EU Foreign Policy Integration by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book The Lean Product Design and Development Journey by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Financial Accounting and Management Control by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Wellbeing, Equity and Education by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Validity and Validation in Social, Behavioral, and Health Sciences by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Rethink! Prototyping by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
Cover of the book Noncolorectal, Nonneuroendocrine Liver Metastases by J. Rick Turner, Dilip R. Karnad, Snehal Kothari
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy