Humana Press: 634 books

A distinguished panel of world authorities reviews the current state of today's understanding, diagnosis, and treatment of pancreatic cancer. Their cutting-edge reviews discuss both medical and surgical modalities and include numerous insights into the basic molecular processes underlying the disease....

New research has shown that neuroendocrine tumors are more common than previously thought.  Progress in our understanding of the molecular pathogenesis of these not-so-rare cancers has resulted in renewed interest in developing innovative therapeutic options.  In particular, novel molecular targeted...

This complete laboratory reference manual explains the principles behind solid phase extraction (SPE) and provides readily reproducible protocols for solving extraction problems in forensic and clinical chemistry. Numerous actual chromatograms, based on original research and diverse applications,...

In recent years there has been a growing recognition that such widely used immunosuppressant drugs as cyclosporin and FK-506 and their analogs-the neuroimmunophilins-possess significant neurotrophic and neuroprotective properties in addition to their beneficial effects for transplant patients. In...

In The Protein Protocols Handbook, I have attempted to provide a cross-section of analytical techniques commonly used for proteins and peptides, thus providing a benehtop manual and guide both for those who are new to the protein chemistry laboratory and for those more established workers who wish...

Thiamine deficiency and related clinical disorders represent an intriguing area of both basic and clinical investigation. Modern imaging strategies have facilitated the rapid treatment, and potential reversal of these clinical disorders. The fusion of laboratory and clinical knowledge serve as an...

A concise, easy-to-read, comprehensive, and up-to-date guide designed to help primary care physicians, pediatricians, and internists with the day-to-day diagnosis and treatment of their allergic patients. Its distinguished contributors-all highly experienced clinicians-integrate our latest understanding...

It has been little more than a century since Emil von Behring and his colleagues (1890) showed that the blood of tetanus-immune rabbits contained a factor that could be transferred to nonimmune animals to protect them against tetanus. These observations, together with the work of Paul Ehrlich, started...

Metal Carcinogenesis Testing explains fundamental principles of metal carcinogenesis as they are currently understood, and provides detailed practical descriptions of rapid and inexpensive in vitro assay methodology presently in use for the detection of potentially carci­ nogenic metals and their...

This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included. Targeted Therapies: Mechanisms of...

Forensic science has come a long way in the past ten years. It is much more in-depth and much broader in scope, and the information gleaned from any evidence yields so much more information than it had in the past because of incredible advances in analytic instruments and crucial procedures at both...

In 1962, Thomas Kuhne coined the term “paradigm shift” while arguing that human knowledge advances by quantum leaps with interspersed smaller steps. Preparation for the major advance is generally not a concerted effort by thought leaders. Rather, a few (or one) visionaries gain insights into a...

Discovery of the BLyS (also known as BAFF) family of ligands and receptors has yielded a paradigm shift in our view of B-lymphocyte selection, survival, activation, and homeostasis. Previously, the B-cell antigen receptor (BCR) was viewed as the sole mediator of these parameters, in which BCR signals...

In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features...